Thalidomide did change myeloma treatment landscape and saved patients lives! #mmsm #medtwitter #myeloma #MedEd #USMIRC 🙏

Wacky new chemistry game: click chemistry or nerve agent?

Having enjoyed the paper from David R. Liu, Fischer Lab, and The Amit Choudhary Lab in Science Magazine this week, we have now posted our own, complementary, taken on a bump-and-hole approach to develop an orthogonal bumped IMiD-degron pair: biorxiv.org/content/10.110….

Stuart Conway Fischer Lab The Amit Choudhary Lab Science Magazine Really lovely and meticulous work, Stuart Conway, using a similar IMiD bump to avoid off-target degradation. It’s possible or even likely that SD40 will interface well with your IMiD, given the relatedness between compound 23 and PT-179, and how the latter is bound in the

Losing Oxford rower reveals he and several others in the boat were struck down with E. coli this morning, apparently from shit in the river. The Boat Race is being watched around the world. The current state of our waterways is an international disgrace and embarrassment.

Join our next TPD Webinar, 2nd May, 11AM EDT/ 8AM PT/ 4PM BST / 5PM CEST Stuart Conway, Patrick Brennan - 'Bringing Bump-and-Hole to Molecular Glues: The Development of Orthogonal IMiD-Degron Pairs' Diane Haakonsen - 'Stress Response Silencing in Neurodegenerative Disease'

Looking forward to a double act with Patrick Brennan on Thursday for the TPD Webinar!

Really enjoying Tame Impala ‘s new album - their poppiest yet. Genius move to have DUA LIPA on vocals

Had a really wonderful time at Centre for Targeted Protein Degradation #TPDFocus conference in Dundee, huge congratulations to Alessio Ciulli & all organisers for putting on such a fantastic event & the official opening of your ‘House of VHL’! Also great to put so many faces to names I’d cited in my thesis!

We have been blown away by all the wonderful messages that we have received in response to our symposium! Thank you! It means a lot to all of us that our delegates had a fantastic time in Dundee and have left inspired to push forward the frontiers of TPD research! #TPDFocus

6 main figs and 5 supplementary figs .

Nature's guide on how to write effective abstracts

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

Sometimes single-minded dedication to a problem is the path to great science. I’ve never met someone more focused on a problem than David Baker. Among the postdocs at UCSF in the early ‘90s, none of us would have been surprised to learn there was a Nobel Prize in David’s future.