We are looking for a couple of Research Technicians to join us in the Fischer Lab! If you enjoy biochemistry/chem bio and are interested in working in a great team exploring degrader induced interactions and degradation reach out or apply:
careers.dana-farber.org/job/research-t…

Please RT!

#AlphaFold can accurately predict PP2A complexes! We solve the structure of #PP2A A R5E C complex and show that PP2A phosphatase assembly is independent of the C subunit methylation. Great team with amazing Franziska Wachter Fischer Lab #Xray
jbc.org/article/S0021-…

Congratulations Franziska Wachter 🎉👏

Just in time for #HumpDay : Our study Targeting DCAF5 suppresses #SMARCB1 -mutant #cancer via stabilizing SWI/SNF is online now in nature. Congratulations 🎉 to co-first authors Sandi-Radko-Juettner and Hong Yue and all co-authors on this story! 1/
nature.com/articles/s4158…

Excited to share E3-substrate tagging by ubiquitin biotinylation (E-STUB) Nature Chemical Biology! E-STUB enables CUL-RING ligase substrate identification and may transform the way we study glues and PROTACs by directly studying substrate ubiquitylation. 1/
rdcu.be/dBZKx

Congratulations Khee Baek 👏🎉

Great to see this story out - congrats to the team 🎉

We are looking for a postdoctoral research fellow to work with Eric Fischer and myself to pioneer next-generation covalent drug discovery. Please retweet. Apply here: careers.dana-farber.org/jobs/?search_t… Fischer Lab

Another incredibly fun Harvard Med BCMP retreat - we decided to become the UPS this year!!

NEWS! I'm excited to share that I'm joining isb_bonn Uniklinik Bonn Rheinische Friedrich-Wilhelms-Universität Bonn ImmunoSensation as a professor to start my LAB! We are open for business and #hiring for #postdoc #tech positions! #NewPI #MoveToGermany #UniBonn #TPD #InducedProximity Please share! nowak-lab.com

Don’t miss out on attending the Keystone Targeted Protein Degradation and Proximity Therapeutics, January 21-24, 2024 🧬⛷️👩‍💻
Abstract deadline is October 26.

Targeted Protein Degradation 
lnkd.in/erkd5Yt4

Proximity Based Therapeutics
lnkd.in/evkF59ga

This week in the TPD seminars we are hosting two excellent speakers Khee Baek and Lukas Teoman Henneberg sharing stories from work completed in Prof. Brenda Schulman's lab at Max Planck Institute for Biochemistry !
See you at 11am EST!!!

We have exciting new updates to our schedule for the free TPD in-person event on September 14th!
Register on our webpage and see you soon!!

Excited to be part of this terrific team with Stegmaier Lab Scott Armstrong Fischer Lab and Ben Ebert at Dana-Farber !Thank you for the opportunity, Cancer Grand Challenges !

This would not have been possible without our wonderful collaborators: Charles Zou, Cristina Di Genua from the Ebert lab and Mikołaj Słabicki 🇺🇦 Dana-Farber; Marius Jentzsch and Jonathan Schmid-Burgk from Rheinische Friedrich-Wilhelms-Universität Bonn; Katherine A Donovan from Fischer Lab

Thank you so much for the support of the MORE trail @Pedalsforpediatrics - special thanks also to my mentors, the study team, collaborators, pedi stem cell transplant team, our patients and their families. Susan Prockop MD Fischer Lab Dana-Farber/Boston Children's

Extremely excited about this event! Join us to meet and chat with other women in TPD and induced proximity!!!

Massive congratulations to Michelle on a beautiful PhD defense this morning and an incredibly productive time in the Fischer lab 🎉🍾

What is protein degradation? Here Fischer Lab provides a really nice and concise summary of what TPD is: youtu.be/slA4s5oaAQk

Very big congratulations to Khee Baek and team on this beautiful work exploring Cullin Ring Ligase biogenesis 🎉
And welcome to the Fischer lab Khee - we are all excited to have you joining us in Boston!!
cell.com/cell/fulltext/…