Adipose iNKT cell subpopulation plays key roles in the control of adipocyte turnover via interaction with adipocytes, adipose stem cells, and macrophages in adipose tissue nature.com/articles/s4146…

still one of the top christmas gifts i have ever received 🧬

Big earthquake hit Japan on New Year’s day, “Gantan”. Hope everyone gets safe.

20-30% of scientists may be using commercial antibodies that don’t work as advertised in their protein studies, potentially skewing results. elifesciences.org/digests/91645/….

Exercise activates immune cells to release Oncostatin-M, which, in turn, instructs fat cells to breakdown fat. Cell Reports Methods cell.com/cell-reports-m…

We are hiring a Research Assistant! Looking forward to a great addition to the Boscolo lab to help with our research on Vascular Anomalies. Contact me if you are interested!

Online now: Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M dlvr.it/T0wVfn

Online Now! A time- and single-cell-resolved model of murine bone marrow hematopoiesis dlvr.it/T11NrN #stemcells

The cover: Inoue et al. explore angiogenic stem/progenitor cell populations. Cover depicts AT-CD271+ prog. (yellow) promoting neovascularization (lectin, green) with engraftment (PKH26, red), and blood flow recovery (cherry blossom). Credit: Oto Inoue & Juan Sanchez-Gurmaches.

Finding more effective therapies for recurrent and refractory acute myeloid leukemia is critically important. We are one of only a few centers in the nation to test a novel therapy that uses CIML-NK cells from haploidentical donors to treat AML. Learn more scienceblog.cincinnatichildrens.org/clinical-trial…

Had a potentially life-changing experience yesterday listening to a talk by @BobFarese and Tobias Walther, 華濤北 and realizing the benefits of having the kind a scientific partnership that comes with having a joint lab. I’m thinking now that I would really love to do that!

If you can commit to a title for your ongoing project.. If you can avoid letting others distract you with unexpected suggestions.. If you can dismiss any emerging contradiction or odd observation, sticking to the original goal.. Then you can be sure that no discovery will happen.

The CPHBAT 2024 program is now accessible on our conference website cphbat.com. A printable PDF version is available at the bottom of the program page. Soren Nielsen Camilla Scheele Zach Gerhart-Hines

Online Now! Long-term engraftment and maturation of autologous iPSC-derived cardiomyocytes in two rhesus macaques dlvr.it/T7szH2 #stemcells

The Metabolism in Action conference is now open for applications! Hope seeing you there in November!! sciencecluster.dk/event/metaboli…

Cardiac shockwave therapy in addition to coronary bypass surgery improves myocardial function in ischaemic heart failure: the CAST-HF trial. Read more in #EHJ 👉 bit.ly/3VzzHT5 Rocco Montone EHJ Editor-in-Chief

Moving from Cincinnati to new place and position😀

Happy to share the final version of our paper describing that the widely used Ucp1-CreEvdr transgene unfortunately elicits complex developmental and metabolic phenotypes. This work was mainly driven by Manasi Halurkar (now a PhD student at Purdue). nature.com/articles/s4146…

This work wouldn't have been possible without the work of BrugmannLab, Hee-Woong Lim and previous and present lab members Oto Inoue, Archana Singh, Rajib Mukherjee and Meghana Ginugu. Cincinnati Children’s Research Cincinnati Children's

We’ve read and discussed: Single-cell transcriptomic landscape of diabetic foot ulcers (PMID: 35013299, Nat Comm 2022) Findings 🔹 Healing DFUs enriched in M1 macrophages and a novel fibroblast population (HE-Fibro) expressing IL6, CHI3L1, MMPs. 🔹 Non-healers had more M2