Our new preprint "Piezo ion channels are capable of conformational signaling" is now live! Conformational changes in Piezo1 ion channels are sensed by other proteins, independently of ion permeation. #Piezos #IonChannels #Biophysics #Neuroscience biorxiv.org/content/10.110…

Emerging from X/Twitter hibernation to announce the first preprint of the lab! Naked mole-rat ❤️ keeps beating without oxygen thanks to their specialised glycogen. Spearheaded by Amanda Bundgaard in collab with FrezzaLab - thanks to all involved! biorxiv.org/cgi/content/sh…

#InCaseYouMissedIt: Last Monday, bioengineering expert Milica Radisic (Milica Radisic) talked about growing vascularized organs on a chip, a challenge she will take on over the next three years during her fellowship at the #mdcBerlin. The full lecture 👉 youtu.be/kOsY_gljItQ

Very happy to announce that our paper showing how voltage block of Piezo2 channels regulates nociceptor excitability is now published in Brain! Great work from Oscar Sánchez-Carranza Oscar Sánchez and colleagues like Sampurna Chakrabarti and Fred Schwaller. academic.oup.com/brain/advance-…

Researchers in Gary Lewin’s lab at #mdcBerlin have identified an ion channel that contributes to chronic pain syndromes, suggesting a new target for pain medications. The study was published in 'Brain.' Brain Manx Neurobiologist Read more: mdc-berlin.de/news/press/und…

Proud to be part of this great job. Congrats Mireia Pàmpols Pérez!

Sanchez-Carranza Manx Neurobiologist and collegues report in Brain that #Piezo2 voltage-block regulates mechanical pain sensitivity doi.org/10.1093/brain/… With Ana Gomis and J Fernandez Trillo Instituto de Neurociencias UMH-CSIC I wrote a commentary on this provocative finding doi.org/10.1093/brain/…

#Piezo1 is also strongly blocked by voltage as nicely shown previously by the labs of Jorg Grandl and Manx Neurobiologist doi.org/10.1016/j.celr… doi.org/10.1038/s41467… Ion channel #biophysics provides important insight into #ionchannel function

Simon Newstead Sigurbjörn Markússon Nuffield Department of Clinical Neurosciences Kavli Institute for Nanoscience Discovery, Oxford Department of Biochemistry at Oxford University Mandy Tseng

Proud to present Alice's Alice Rossi exciting study on how unique molecular adaptations of mitochondrial proteins allow naked mole-rat cells to survive 2 days without oxygen! Sociality shapes mitochondrial adaptations supporting hypoxia tolerance biorxiv.org/content/10.110…

KI researchers have developed a comprehensive pain atlas, iPain, now available on CellxGene. The atlas, presented Nature Communications, offers valuable resources for future pain research and opens way to better treatment for #ChronicPain and #headache disorders. news.ki.se/new-study-brin…

October's issue of Brain is now online! academic.oup.com/brain/issue/14…

☀️ Good morning, everyone! This week's #MicrogliaResearch in Health and Disease is now available! #Neuroscience #Aging As a scientist passionate about Microglia, I'm excited to share my curated selection of publication highlights with you each week. Discover the complete list

Piezo2 channels and tactile pain: an intriguing voltage connection New scientific commentary by Jorge Fernández-Trillo, Ana Gomis and Félix Viana academic.oup.com/brain/article/…

👋 Good morning, everyone! This week's #MicrogliaResearch in Health and Disease, supported by Bims: Biomed News, is now available! #Neuroscience #Aging As a scientist passionate about microglia, I’m excited to share my curated selection of publication highlights with you each

Sociality shapes mitochondrial adaptations supporting hypoxia tolerance biorxiv.org/content/10.110… 👇 Below a twittorial on Alice Rossi's great paper Alice Rossi describing the mechanisms of cellular hypoxia resistance in the naked mole-rat!👇

TENM4 is an essential transduction component for touch and pain biorxiv.org/content/10.110…