After four years of user feedback and experience, our NicheNet best practices guideline is now available on arXiv! arxiv.org/abs/2404.16358 Also check out our revamped GitHub repository that incorporates these changes: github.com/saeyslab/niche… (1/2)

OPEN DRY LAB PhD POSITION! Join the KU Leuven BREATHE lab's ILD team to investigate pulmonary fibrosis (PF) using ultra-high resolution #CT & #microCT and single cell & spatially resolved #transcriptomics and #proteomics. Want to join? Apply here: kuleuven.be/personeel/jobs…

Are you a medical student looking to gain experience in a translational science laboratory? We have an open position as part of the structured clinician-scientist program at the Institute of Lung Health and Immunity . Join us to acquire a broad range of practical and theoretical laboratory skills!

Great overview in Cell on Immune mechanisms in fibrotic interstitial lung diseases - lots of progress in elucidating fibroblast and epithelial plasticity in recent years, but role of the immune system in pulmonary fibrosis is understudied ... doi.org/10.1016/j.cell…

Happy to announce our new research unit `Precision Regenerative Medicine´ Helmholtz Munich | @HelmholtzMunich. We study mechanisms of failed regeneration in the aging process and chronic lung diseases and work towards regenerative reprogramming therapy. website: helmholtz-munich.de/en/prm

I'm stoked to announce our new end-to-end framework for perturbation analysis! Our scverse advisory committee highlighted that a maintained and well-documented framework for perturbation analysis is missing. Pertpy is our attempt to satisfy this request biorxiv.org/content/10.110…

Super excited to share our latest work on immune-epithelial interactions in lung fibrosis post COVID-19! This would not be possible without the invaluable help from all the co-authors and our collaborators - Thank you! Read below for more info! nature.com/articles/s4158… (1/11)

Last day on the wards as a med student! Now, time to focus on finals so I can return as a physician soon :) Grateful for all I’ve learned during my elective year in Zürich & Basel 🙏 Plus, I got to share some magic moments with old and new friends high up in the alps! 🇨🇭🏔️

I am now also on bluesky: bsky.app/profile/lukash… Trying to rebuild my network there now...

I joined BlueSky - please follow me there bsky.app/profile/niklas… Let’s build a thriving single cell & lung biology community there! 🫁💪

Exciting paper in Nature Cardiovascular Research: venous ECs branch and differentiate into capillary ECs to regenerate the alveolar gas exchange unit following lung injury - but NOT in fibrotic (KRT5+) or AT1 depleted regions - some food for thought: nature.com/articles/s4416…

Huge milestone today: thesis submitted 🎉 Universität München Helmholtz Munich | @HelmholtzMunich — and first day of clinical training UniSpitalBaselCH! Grateful and excited for what’s ahead 🙌

1/n Using snRNAseq we identify a previously undiscovered population of alveolar epithelial cells in IPF - Alveolar Intermediate (ATi) cells - they share features of ATI, ATII and Aberrant Basaloid cells but also have their own distinct features. #ATi biorxiv.org/content/10.110…