 
                                Jerome Staal
@neurostaal
Neuro-glia scientist, interested in brain development, plasticity and neurodegeneration.
Editor @NatureMedicine -- Opinions are my own
ID: 4707750373
04-01-2016 08:06:13
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        🌟Exciting new study show that that somatic CAG repeat expansion measured longitudinally in blood is a key driver of the effect of CAG repeat length on markers of very early #neurodegeneration in #HuntingtonsDisease. UCL Huntington’s Disease Centre UCL Queen Square Institute of Neurology nature.com/articles/s4159…
 
         
         
        🔬 New study from @tommykakari and colleagues identifies a core amino acid sequence that defines pre-tangle tau aggregates, revealing phospho-tau serine-262 & serine-356 as novel early-stage biomarkers. #Tau #Alzheimers #Biomarkers #EarlyDetection Pitt Psychiatry
 
                        
                    
                    
                    
                 
        A rare case of asymptomatic dominantly inherited #Alzheimer's reveals confined tau pathology and unique proteomic features, highlighting potential resilience mechanisms decades beyond expected onset. WashU Medicine Knight ADRC Jorge Llibre-Guerra dlvr.it/THwPpj #Resilience
 
         
        Check out #February's Editorial in Nature Medicine highlighting the potential of #DementiaPrevention approaches to combat the rising incidence of #dementia and the need for more #ClinicalTrials. #Alzheimers #AD #Prevention #Aging dlvr.it/TJ5FXD
 
        Great new study out in Nature Medicine identifies #Plasma eMTBR-tau243 as a specific #biomarker of #tau tangles in #Alzheimers disease, enabling the detecting and tracking of Alzheimer’s clinical impairment. #ADPD2025 nature.com/articles/s4159…
 
        #Education is linked to better #memory and larger brain volumes, but not to slower cognitive or #brain decline with age—suggesting the association reflects early-life factors rather than neuroprotective effects in #aging Anders Martin Fjell LCBC - UiO nature.com/articles/s4159…
 
         
         
        🧪A quick, self-administered #DigitalTest can accurately detect #AlzheimersDisease in #PrimaryCare, outperforming traditional methods and empowering earlier, more precise diagnoses. Oskar Hansson Linda Karlsson nature.com/articles/s4159…
 
         
        One of the most serious yet often overlooked consequences of #SpinalCordInjury is #BloodPressure instability. A new #spinalcordstimulation system now demonstrates the ability to prevent hypotensive episodes and enhance patients' quality of life G Courtine nature.com/articles/s4159…
 
         
         
         
         
         
                         
                         
                         
                        