You knock out #GLUT1 to impair astrocytic glucose uptake - only to find out that #astrocytes ramp up glycolysis and keep going. Metabolically resilient, and even neuroprotective. Our study in Nature Communications: nature.com/articles/s4146…

Online now: Selectively vulnerable deep cortical layer 5/6 fast-spiking interneurons in Alzheimer’s disease models in vivo dlvr.it/TKdvw6

AQUA2: My favorite analysis toolbox for astrocyte It is so exciting to analyze the data with this one. I really appreciate their contribution to scientific community! github.com/yu-lab-vt/AQuA2 cell.com/cell/fulltext/…

1/12. How do cortical interneurons select specific pyramidal cells during development? Julie Jezequel in Beatriz Rico has identified specific cellular and molecular codes that interneurons use to target pyramidal cell types Nature Communications CDN | King's College CNDD| King's College Institute of Psychiatry, Psychology & Neuroscience

Astrocytes have long been conceived as passive support player cells in the brain. But today Science Magazine (via 3 reports) they got a big upgrade for their active role in neuromodulation and control of brain function science.org/doi/10.1126/sc…

Delighted to see not one, not two, but three papers about astrocytes in Science today! Here's our contribution to that collection. Come follow us on bluesky! Papouin lab twitter/X: over & out... science.org/doi/10.1126/sc…

Do we need to rethink near-death experiences? What’s really happening in the brain? NDEs might be a hardwired coping strategy: the dissociation, calmness, and detachment when facing death may actually be an evolutionarily protective response. For decades, people have asked me:

Despite a decrease in age-standardized rates, subarachnoid hemorrhage remains one of the most common cardiovascular and neurological causes of death and disability globally. #ESOC2025 European Stroke Org ja.ma/4mtU40w

Using multi-modal imaging, Kozberg et al. report that loss of vasomotion occurs early in cerebral amyloid angiopathy in a mouse model. This loss coincided with initial vascular amyloid-β deposition and preceded the occurrence of microbleeds. Read at buff.ly/duW26H0

Our new paper with Applied Cognition in Nature Biomedical Engineering . Using a wearable device that captures different determinants of glymphatic activity to define sleep-related features of glymphatic function in the human brain. nature.com/articles/s4155…

In Science Magazine today, my essay on predicting and preventing Alzheimer's disease (open-access) science.org/doi/10.1126/sc…

PhD defense done! I sincerely appreciate my PI and mentor KIM Sun Kwang, and I also want to thank all my lab members.

NPTX2 is emerging as a key neurodegeneration biomarker, but measurement tools are limited. We developed a low-volume, automated Simoa assay for its quantification in CSF #biomarkers #neurodegeneration pubmed.ncbi.nlm.nih.gov/40522075/

🚨 #HotTopic: New insights into brain waste clearance revealed by in vivo 2-photon imaging! How does focused ultrasound + microbubbles enhance glymphatic transport? Find out in this study 👉🏻 journals.sagepub.com/doi/full/10.11… #ISCBFM #Neuroscience #Glymphatic #FUSMB #BrainHealth

Excited to share our latest Review on three-photon microscopy in the neurosciences - out today in Nature Rev Neurosci ! Hopefully this will help spread this powerful deep-imaging technique even further. Access here: rdcu.be/er5SZ Thanks to all co-authors!

Asymmetric distribution of mitochondrial Ca2+ regulators specifies compartment-specific mitochondrial function and neuronal development biorxiv.org/content/10.110… #biorxiv_neursci

Photothrombotic Ischemic Thalamic Stroke in Mice Recapitulates Spontaneous Pain Features of Central Post-Stroke Pain in Humans biorxiv.org/content/10.110… #biorxiv_neursci

We are excited to report: Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IP3R2-mediated Ca2+ signaling in mice Vittani et al. PNAS (2025) pnas.org/doi/10.1073/pn…

Curious about diving into astrocyte Ca²⁺ signaling with two-photon microscopy? Check out our newly published step-by-step protocol! Micaela Zonta Bio-protocol 🧠 #astrocyte #imaging #neuroscience #brainslices #calcium bio-protocol.org/en/bpdetail?id…

Folks, the video abstract on this paper is a masterpiece cell.com/current-biolog… H/t Urszula Skupio