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#Comment Wildfires emit carcinogenic pollutants, raising long-term cancer risks in affected populations. In this Comment, Weichenthal McGill University highlights these concerns and outlines actionable solutions to reduce exposure and mitigate risks. bit.ly/4cgXm2L

NEW content online! Phosphoinositide kinases in cancer: from molecular mechanisms to therapeutic opportunities bit.ly/4iQunoF

NEW content online! Blocking cholesterol biosynthesis to clean out cancer bit.ly/3RG16B7

Looking for some #weekendreading? In this #Review, Luri-Rey et al. present evidence for the crucial role of conventional type 1 dendritic cells in cross-priming CD8+ T cells for effective anti-cancer immunity. Read it here 👇 bit.ly/4cj4RWF

NEW content online! TurboCas for locus-specific proximity labelling bit.ly/3YnLbv3

🚨 Comment 🚨 Virginie Stévenin & Jacques Neefjes Leiden University highlight the need to understand the mechanisms by which Salmonella infections, whihc correlate with increased cancer risk, drive cellular transformation. 📖 ⬇️ bit.ly/3E9xNnD

#Tools of the Trade 🚨 Ziwei Xue Zhejiang University describes the development and use of #scAtlasVAE, a deep learning framework integrating #scRNA-sequencing data from CD8+ T cells across studies. 📖 ⬇️ bit.ly/4ibdpAq

NEW content online! Challenges of small cell lung cancer heterogeneity and phenotypic plasticity bit.ly/4conLvs

Looking for some #WeekendReading material? 🚨 Check out this #REVIEW by Zhimin Lu & Co Zhejiang University discussing how non-canonical functions of glucose metabolic enzymes can help drive cancer progression. 📖 ⬇️ bit.ly/4cpbSoW

#ResearchHighlight 🚨 In a recent study published in Nature Communications Chen et al. demonstrate that the cholesterol biosynthesis protein CYP51A1 suppresses #alkaliptosis induced by the opioid analgesic JTC801. 📖 ⬇️ bit.ly/3XX2cw5

#Tools of the Trade 🚨 Bercin Cenik Bercin K Cenik Northwestern Feinberg School of Medicine describes the development and use of #TurboCas, a locus-specific proximity labelling enzyme to map the regulatory proteins that shape transcription. bit.ly/4lx8r3K 📖 ⬇️ @nufeinbergmed.bsky.social

NEW content online! CRISPR-StAR to transform in vivo functional genomic screening bit.ly/4jEcz0j

#REVIEW 🚨 Brooke Emerling & Co @SBPdiscovery summarize the roles of phosphatidylinositol 4-kinases #PI4Ks and phosphatidylinositol phosphate kinases #PIPKs in cancer. 📖 ⬇️ bit.ly/3GezCQY

🐰#Weekendrreading #Review🚨 Caroline Dive&Co discuss the challenges associated with #ITH and plasticity in #SCLC and argue that combination therapies&liquid biopsy-based biomarkers are needed to improve patient outcomes. 📖⬇️ CRUK Manchester Institute CRUK Lung Centre bit.ly/4cBDZ4D

NEW content online! Evolutionary paths towards metastasis bit.ly/44CuS1n

NEW content online! Measuring HLA disruption using MHC Hammer bit.ly/42NlIgh

🚨 #Tools of the Trade 🚨 Christopher Lowden describes the development and use of #CRISPR-StAR, which leverages internal controls to overcome experimental noise for improved in vivo functional genomic screens. 📖 ⬇️ bit.ly/3EzFPX0

NEW content online! Androgen receptor activation for breast cancer therapy bit.ly/4jMk31c

NEW content online! Targeted protein degradation for cancer therapy bit.ly/3RxKZG3