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Our latest review on "Neuroimmune pathophysiology of long COVID" is out today! Amazing work of janna moen, phd is still masking 😷 and Christopher A. Baker 👏🏼👏🏼👏🏼 It is open-access; please share widely. #Neuroimmune #PAIS #LongCovid onlinelibrary.wiley.com/doi/10.1111/pc…

Activation of macrophages engulfing neutrophils by TNF switches efferocytosis to caspase-8–mediated pyroptosis and IL-1β production Science Immunology Poltorak Lab science.org/doi/10.1126/sc…

Lilly’s Bimagrumab blocks the receptor for myostatin and activin A. In a prior Phase 2, Bimagrumab helped T2D patients lose fat mass while increasing lean mass. Lilly hopes that a strong anabolic agent like bimagrumab can help achieve pure fat mass loss, but avoid the safety

🚫 No dyes. No bleaching. 🔬 Just AI + label-free microscopy = vivid virtually stained images New in Nature Machine Intelligence: A deep learning model that enables robust virtual staining across microscopes, cell types & conditions. #CZBiohubSF Shalin Mehta explains:

12. Carrie: I'm the lost tribe & was lost in the system. My diagnosing doctor was right in 2009. I had sacroiliitis. Then met a doc who believed women don’t get AS. He stopped my AS treatments. That caused unspeakable damage to me patient! @Spondylitis #SpondySummit #Spondylitis

In Science, researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells. The approach showed rapid and sustained immune reprogramming in preclinical models,

Comparison of the Definitions of the Complex to Manage -by GRAPPA- and Difficult to Manage -by EULAR- #Psoriatic_Arthritis As presented at #EULAR2025 by Dr Fabian Proft OP0175 & Dr Helena Marzo-Ortega at the recommendations session Two Frameworks for One Challenge Dr. John Cush

Management of hidradenitis suppurativa in UK primary care: cross-sectional survey bjgpopen.org/content/bjgpoa…

Tertiary lymphoid organs are lymph node-like structures observed in certain inflammatory diseases. Geng, Sathish Srinivasan et al. OMRF demonstrate that S1PR1 activity in the lymphatic vasculature is necessary to prevent TLO formation in the terminal ileum. hubs.la/Q03tn3v00

Manipulating condensation of thermo-sensitive SUF4 protein tunes flowering time in Arabidopsis thaliana dlvr.it/TLZRT1

So happy to finally see our paper published! 🥂 If you're interested in plasmid biology, check it out! 👀🧬

The eukaryotic tRNA chaperone La impacts tRNA modification levels (queuosine and others). Interesting because in procaryotes, tRNA modif enzymes themselves are thought to be chaperones. In both cases, there seems to be a link between modif and chaperones. academic.oup.com/nar/article/53…

A fascinating new study by Vishnu Shankar et al. Stanford Immunology shows that oxidative stress is a shared characteristic of ME/CFS and Long COVID in lymphocytes due to inability to clear reactive oxygen species. This happens in sex-specific manner. (1/) pnas.org/doi/abs/10.107…

An Asgard archaeon from a modern analog of ancient microbial mats biorxiv.org/content/10.110… #biorxiv_micrbio

“An Asgard archaeon produces chains of vesicles attached to the cell by extracellular fibers, and intracellular tube- & cage-like structures A bacteria symbiont assembles intercellular nanotubes thru which both species interact May reflect an early step in eukaryotic evolution”

Many proteins bind RNA, yet we still don’t know what RNAs most bind because methods map one RBP at a time. In Cell, with the Jovanovic lab, we describe SPIDR – a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. sciencedirect.com/science/articl…

Can the immune system be activated by imaginary germs? Study finds that visual proximity with an object perceived as infections is sufficient for triggering an immune response. nature.com/articles/s4159…

tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa 🦠👏High-throughput tRNA epitranscriptome profiling using mass spec on P. aeruginosa transposon insertion library and links with metabolic networks doi.org/10.1093/nar/gk…

And you thought #metformin lowered glucose via the liver? Here loss-of-function and gain-of-function studies suggest that VMH Rap1 is indispensable for the antidiabetic effects of metformin in mice #diabetes science.org/doi/10.1126/sc…

Gut Bacteria Proteins Offer Clues to Chronic Disease Therapies The data shows that RORDEP-proteins boost the production of hormones like GLP-1 and PYY, which help regulate appetite and blood sugar levels University of Copenhagen #gutflora #microbiome #diabetes hubs.li/Q03zRRb-0