Earlier this year, we had the pleasure of installing a Patchliner in the lab of Dr. Jaideep Cherakka Kesavan at Dublin City University. Dr. Kesavan’s research bridges neuroscience, stem cell biology, and purinergic signaling. His recent work focuses on: ▪️The functional role of

Lysosomal Ion Channels and Transporters: Recent Findings, Therapeutic Potential, and Technical Approaches | Bioelectricity liebertpub.com/doi/10.1089/bi…

The epithelial sodium channel (#ENaC) plays a central role in regulating sodium balance, blood pressure, and pulmonary fluid clearance. Despite its clinical relevance, progress in discovering new ENaC-targeting drugs has been limited by the lack of efficient, scalable functional

𝗪𝗲𝗯𝗶𝗻𝗮𝗿 𝗮𝗹𝗲𝗿𝘁: 𝗘𝘅𝗽𝗹𝗼𝗿𝗶𝗻𝗴 𝗰𝗵𝗮𝗻𝗻𝗲𝗹𝗼𝗽𝗮𝘁𝗵𝗶𝗲𝘀 𝗮𝗻𝗱 𝗹𝘆𝘀𝗼𝘀𝗼𝗺𝗮𝗹 𝘁𝗮𝗿𝗴𝗲𝘁𝘀 𝘄𝗶𝘁𝗵 𝘁𝗵𝗲 𝗦𝘆𝗻𝗰𝗿𝗼𝗣𝗮𝘁𝗰𝗵 𝟯𝟴𝟰 Whether you're investigating rare channelopathies or pursuing lysosomal ion channels as drug targets, this

𝗧𝗵𝗲 𝗖𝗮𝗿𝗱𝗶𝗮𝗰 𝗦𝗮𝗳𝗲𝘁𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝟮𝟬𝟮𝟱 𝗶𝘀 𝗮𝗹𝗺𝗼𝘀𝘁 𝗵𝗲𝗿𝗲! Two days to go — Are you in? 📅 This Wednesday, May 21 📍 Online & free to attend If you're working in cardiac safety, drug development, or electrophysiology, this is your chance to catch

Studying ion channels inside organelles was once a technical challenge. Now, it's opening up new possibilities in both research and drug development. These intracellular channels regulate key processes like calcium signaling, autophagy, and pH balance. They're also linked to

𝗛𝗼𝘄 𝘄𝗲𝗹𝗹 𝗱𝗼 𝘄𝗲 𝗿𝗲𝗮𝗹𝗹𝘆 𝘂𝗻𝗱𝗲𝗿𝘀𝘁𝗮𝗻𝗱 𝘁𝗵𝗲 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻𝗮𝗹 𝗶𝗺𝗽𝗮𝗰𝘁 𝗼𝗳 𝗖𝗮𝗩𝟭.𝟮 𝗺𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝘀? Join us on June 12 to explore new insights Join us for an exciting session featuring the 2023 SyncroPatch 384 Research Grant winners from the

𝗜𝗼𝗻 𝗰𝗵𝗮𝗻𝗻𝗲𝗹𝘀 𝗶𝗻 𝗴𝗲𝗻𝗲 𝘁𝗵𝗲𝗿𝗮𝗽𝘆: Altering expression to treat channelopathies and chronic diseases As gene therapy moves from concept to clinic, ion channels are finally part of the picture, with applications across pain, epilepsy, and rare genetic diseases.

Thanks very much FASEB for organising such a lovely press release on our latest article, and helping spread the word to reach new readers😊! Check it out👇 "Proper Folding Is Important for a Protein Associated with Seizures" newswise.com/faseb/proper-f… Nanion Technologies MedUni Wien

𝗧𝗵𝗲 𝗠𝗲𝗺𝗯𝗿𝗮𝗻𝗲 𝗣𝗵𝘆𝘀𝗶𝗼𝗹𝗼𝗴𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝗶𝘀 𝗰𝗼𝗺𝗶𝗻𝗴 𝘁𝗼 𝗧𝗼𝗸𝘆𝗼 𝘁𝗵𝗶𝘀 𝗝𝘂𝗹𝘆! Following the success of the two editions of the Membrane Physiology Symposiums in California, we’re excited to bring the series to Japan for the very first time!

𝗧𝗵𝗲 𝗦𝘆𝗻𝗰𝗿𝗼𝗣𝗮𝘁𝗰𝗵 𝟯𝟴𝟰 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗚𝗿𝗮𝗻𝘁 𝗶𝘀 𝗯𝗮𝗰𝗸 𝗳𝗼𝗿 𝟮𝟬𝟮𝟱! What if you had 384 skilled patch clamp electrophysiologists working for you? After the success of our 2021 and 2023 editions, we’re excited to launch the 2025 SyncroPatch 384

𝗖𝗮𝗻 𝘄𝗲 𝗿𝗲𝘀𝘁𝗼𝗿𝗲 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻 𝘁𝗼 𝗲𝗽𝗶𝗹𝗲𝗽𝘀𝘆-𝗹𝗶𝗻𝗸𝗲𝗱 𝗚𝗔𝗧-𝟭 𝗺𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝘀? Mutations in the GABA transporter GAT-1 (SLC6A1) are linked to epilepsy and neurodevelopmental disorders. This study takes a closer look at two variants affecting

𝗛𝗼𝘄 𝗰𝗮𝗻 𝘄𝗲 𝗯𝗲𝘁𝘁𝗲𝗿 𝗽𝗿𝗲𝗱𝗶𝗰𝘁 𝗰𝗮𝗿𝗱𝗶𝗮𝗰 𝗱𝗿𝘂𝗴 𝗿𝗲𝘀𝗽𝗼𝗻𝘀𝗲𝘀? By combining electrophysiology, contractility, and cell viability into a unified workflow, researchers gain a more complete picture of cardiac function, electrical, mechanical, and

𝗖𝗮𝗻 𝗮 𝗻𝗮𝘁𝘂𝗿𝗮𝗹 𝗰𝗼𝗺𝗽𝗼𝘂𝗻𝗱 𝘁𝗮𝗿𝗴𝗲𝘁 𝗱𝗿𝘂𝗴-𝗿𝗲𝘀𝗶𝘀𝘁𝗮𝗻𝘁 𝗰𝗮𝗻𝗰𝗲𝗿? Colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) remain among the most deadly cancers worldwide. EGFR-targeted therapies can offer initial benefits, but resistance

𝗛𝗼𝘄 𝗱𝗼 𝘆𝗼𝘂 𝗲𝘅𝘁𝗿𝗮𝗰𝘁 𝗿𝗲𝗮𝗹 𝗺𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝘁𝗶𝗰 𝗶𝗻𝘀𝗶𝗴𝗵𝘁 𝗳𝗿𝗼𝗺 𝗦𝗼𝗹𝗶𝗱 𝗦𝘂𝗽𝗽𝗼𝗿𝘁𝗲𝗱 𝗠𝗲𝗺𝗯𝗿𝗮𝗻𝗲 𝗘𝗹𝗲𝗰𝘁𝗿𝗼𝗽𝗵𝘆𝘀𝗶𝗼𝗹𝗼𝗴𝘆 (𝗦𝗦𝗠𝗘) 𝘀𝗶𝗴𝗻𝗮𝗹𝘀? Join us for a live webinar with Dr. Andre Bazzone where he will introduce a

𝗡𝗼𝘄 𝗮𝘁 𝗨𝗖𝗦𝗙: 𝗙𝗶𝗿𝘀𝘁 𝗦𝗨𝗥𝗙𝗘²𝗥 𝗡𝟭 𝗦𝘆𝘀𝘁𝗲𝗺 𝗼𝗻 𝘁𝗵𝗲 𝗨.𝗦. 𝗪𝗲𝘀𝘁 𝗖𝗼𝗮𝘀𝘁 We’re thrilled to announce that the first SURFE²R N1 system is now installed at University of California San Francisco (UCSF), expanding access to label-free transporter

𝗪𝗼𝘂𝗹𝗱𝗻’𝘁 𝘆𝗼𝘂 𝗹𝗶𝗸𝗲 𝟯𝟴𝟰 𝗽𝗮𝘁𝗰𝗵 𝗰𝗹𝗮𝗺𝗽 𝗲𝘅𝗽𝗲𝗿𝘁𝘀 𝗶𝗻 𝘆𝗼𝘂𝗿 𝗹𝗮𝗯? Now you can, with the SyncroPatch 384 Research Grant. Every researcher has that one project: ▪️ Waiting for the right time (and the right tools) ▪️ A new target you’ve been

𝗨𝗻𝗽𝗿𝗲𝗰𝗲𝗱𝗲𝗻𝘁𝗲𝗱 𝗳𝗹𝗲𝘅𝗶𝗯𝗶𝗹𝗶𝘁𝘆 𝗳𝗼𝗿 𝗛𝗧𝗦 𝗮𝘂𝘁𝗼𝗺𝗮𝘁𝗲𝗱 𝗽𝗮𝘁𝗰𝗵 𝗰𝗹𝗮𝗺𝗽 Ion channel research is complex, and every project brings different demands. Some days are all about throughput. Others require fine-tuned control for assay development or

𝗦𝗰𝗶𝗲𝗻𝗰𝗲, 𝗰𝗼𝗻𝗻𝗲𝗰𝘁𝗶𝗼𝗻𝘀, 𝗮𝗻𝗱 𝗹𝗶𝘃𝗲 𝘄𝗼𝗿𝗸𝘀𝗵𝗼𝗽𝘀: Highlights from the Membrane Physiology Symposium Japan On July 17–18, we held the first-ever Membrane Physiology Symposium (MPS) in Japan, organized in collaboration with Prof. Hideaki Kato and his lab