LVAD explant after myocardial recovery❓ US data showed that: ➡️ 5-10% incidence for LVAD explant following myocardial recovery at selected centers🏥 ➡️ Over half sustain the🫀function and off transplant list Details: jacc.org/doi/10.1016/j.… #JACCHF JACC Journals

🔥 Off the Press! New HCM Guidelines

First #LBCT of #HeartFailure2024 Timing of Cardio-Kidney Protection w #SGLT2i: Insights From 4 Large-Scale Placebo-Controlled RCTs HF is THE most modifiable and preventable event across #CKM Simultaneous publication led by Brendon Neuen in Circulation ahajournals.org/doi/10.1161/CI…

A big day for treatment of obstructive #HCM. We now have a second treatment option in the #myosininhibitor class. Amazing data. Grateful to have contributed and more data are coming! Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy: nejm.org/doi/full/10.10…

Once again, nice work Neal Dixit, MD . I often start SGLT2- and MRA first as easy to get to targeted dose fast. Now its cost effective too!

Me: Dear 🫀universe, I would like a state of the art paper to contextualize new aficamten data from #HFA2024 in HCM Journal of Cardiac Failure: I got you 😉💜 👇🏽👇🏽👇🏽HFSA ColumbiaCardiology

Can novel smartphone applications using accelerometer + gyroscope measurements be used to detect HF? Insight into the high accuracy algorithms using motion sensors from smartphones to detect HF 📱 REFLECS study now in JACC Journals #JACCHF 📎 jacc.org/doi/10.1016/j.…

New in #jacchf ⭐️Role of Palliative Care Across HF Improves ⬆️ Sx Control ⬆️ QOL ⬆️ Caregiver satisfaction ⬇️ Caregiver Anxiety. 🔑 Limited Palliative care workforce ✅ Novel Palliative Care models are needed to met needs to improve care of HF pts JACC Journals #JACCHF

How to define #PreHF stage⁉️ Dr #AntoniBayesGenis and BiykemBozkurt proposed 3 categories to define this grey area: 1️⃣Structural Heart Abnormalities -🫀structural/functional issue w/o ⬆️ NPs - e.g: LVH, chambers enlargements, wall motion abnormalities 2️⃣Heart Stress -⬆️#Biomarkers

#GDMTworks, but we still aren't using it. New in #JACCHF: in 40K pts w newly dx #HFrEF, slow uptake on GDMT initiation w disparity btwn rural & urban use. 16% excess mortality risk for rural pts. *We can do better* 👀:jacc.org/doi/10.1016/j.… JACC Journals Gregg Fonarow MD ambarish

We are pleased to share positive topline results from our HELIOS-B Phase 3 study of vutrisiran, an investigational #RNAi therapeutic in development for the treatment of #ATTR #amyloidosis w/ cardiomyopathy. Read the press release: bit.ly/3VwvRtY #RNAiTherapeutics #siRNA

CLOROTIC Trial: Adding HCTZ to IV furosemide seems to be an effective strategy for improving diuretic response in AHF across the spectrum of EF: similarly in HFrEF, HFmrEF and HFpEF. in #JACCHF jacc.org/doi/10.1016/j.… JACC Journals Marta Sánchez Joan Carles Trullàs, MD, PhD

New review in #JACCHF by Kieran Docherty on the treatment and prevention of HF following AMI. * Review of current evidence and guideline recommendations * Discussion of ongoing research * Proposal to identify highest risk pts to guide tx 🔥Don't miss!! jacc.org/doi/10.1016/j.…

New 📄 in JACC Journals #JACCHF ❓Objective: Compare Health Care QOL (HFQOL) in HF vs Cancer 🫀 Methods: Analysis Medicare 2016-2000 🎯Conclusions: People with HF ⬇️ HFQOL than those with Cancer actively receiving tx. Read More 👇🏼 📎 jacc.org/doi/abs/10.101…

This combined data from #TRITON & #REPAIR studies (N=148) on initial macitentan + tadalafil therapy shows; 📍#PVR reduction: -55% (no comorbidities) & -50% (1-2 comorbidities) at Week 26 📍Functional improvements observed, lesser extent in comorbid patients 📍Majority improved

In HFrEF, lack of therapeutic urgency is: 🌎 Common 💵 Costly ☠️ Deadly Published in Circulation, 5 core "take-home" principles for rapid & intensive #GDMT as a foundational approach doi.org/10.1161/CIRCUL… Steve Greene Javed Butler

New in #JACCHF: 🔥 Obesity & Weight Loss Strategies for Patients with Heart Failure Nice review of this important target in the management of #HF JACC Journals JACC HF: jacc.org/doi/10.1016/j.…

🔥🔥 ☠️ for phenotypes along preshock -> CS continuum 👉 jacc.org/doi/full/10.10… JACC Journals #JACCHF Critical Care Cardiology Trials Network 🎯 Hypoperfusion +/- hypotension -> ⬆️☠️ 🎯 normotensive CS -> distinct CS phenotype 🎯 Identify pre-& early shock to improve #CardiogenicShock outcomes