Munir S Janmohamed MD FACC, FHFSA (@munirjanmohamed) 's Twitter Profile
Munir S Janmohamed MD FACC, FHFSA

@munirjanmohamed

Medical Director Heart Failure/LVAD Program Mercy Medical Group Cardiology/Mercy General Hospital #JACCHF SoMe Editorial Team

ID: 263426589

linkhttp://instagram.com/drmunirjanmohamed calendar_today10-03-2011 01:07:00

368 Tweet

805 Followers

361 Following

Novi Tham (@slumberbell) 's Twitter Profile Photo

LVAD explant after myocardial recovery❓ US data showed that: ➡️ 5-10% incidence for LVAD explant following myocardial recovery at selected centers🏥 ➡️ Over half sustain the🫀function and off transplant list Details: jacc.org/doi/10.1016/j.… #JACCHF JACC Journals

LVAD explant after myocardial recovery❓

US data showed that:
➡️ 5-10% incidence for LVAD explant following myocardial recovery at selected centers🏥
➡️ Over half sustain the🫀function and off transplant list

Details: jacc.org/doi/10.1016/j.…

#JACCHF <a href="/JACCJournals/">JACC Journals</a>
Muthu Vaduganathan (@mvaduganathan) 's Twitter Profile Photo

First #LBCT of #HeartFailure2024 Timing of Cardio-Kidney Protection w #SGLT2i: Insights From 4 Large-Scale Placebo-Controlled RCTs HF is THE most modifiable and preventable event across #CKM Simultaneous publication led by Brendon Neuen in Circulation ahajournals.org/doi/10.1161/CI…

First #LBCT of #HeartFailure2024

Timing of Cardio-Kidney Protection w #SGLT2i: Insights From 4 Large-Scale Placebo-Controlled RCTs

HF is THE most modifiable and preventable event across #CKM

Simultaneous publication led by <a href="/brendonneuen/">Brendon Neuen</a> in <a href="/CircAHA/">Circulation</a> 
ahajournals.org/doi/10.1161/CI…
James Januzzi Jr MD (@jjheart_doc) 's Twitter Profile Photo

A big day for treatment of obstructive #HCM. We now have a second treatment option in the #myosininhibitor class. Amazing data. Grateful to have contributed and more data are coming! Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy: nejm.org/doi/full/10.10…

Anu Lala-Trindade (@dranulala) 's Twitter Profile Photo

Me: Dear 🫀universe, I would like a state of the art paper to contextualize new aficamten data from #HFA2024 in HCM Journal of Cardiac Failure: I got you 😉💜 👇🏽👇🏽👇🏽HFSA ColumbiaCardiology

Me: Dear 🫀universe, I would like a state of the art paper to contextualize new aficamten data from #HFA2024 in HCM

<a href="/JCardFail/">Journal of Cardiac Failure</a>: I got you 😉💜

👇🏽👇🏽👇🏽<a href="/HFSA/">HFSA</a> <a href="/CU_Cardiology/">ColumbiaCardiology</a>
Nikhil Narang, MD (@nikhil15) 's Twitter Profile Photo

Can novel smartphone applications using accelerometer + gyroscope measurements be used to detect HF? Insight into the high accuracy algorithms using motion sensors from smartphones to detect HF 📱 REFLECS study now in JACC Journals #JACCHF 📎 jacc.org/doi/10.1016/j.…

Can novel smartphone applications using accelerometer + gyroscope measurements be used to detect HF?

Insight into the high accuracy algorithms using motion sensors from smartphones to detect HF 📱 

REFLECS study now in <a href="/JACCJournals/">JACC Journals</a> #JACCHF 

📎 jacc.org/doi/10.1016/j.…
Munir S Janmohamed MD FACC, FHFSA (@munirjanmohamed) 's Twitter Profile Photo

New in #jacchf ⭐️Role of Palliative Care Across HF Improves ⬆️ Sx Control ⬆️ QOL ⬆️ Caregiver satisfaction ⬇️ Caregiver Anxiety. 🔑 Limited Palliative care workforce ✅ Novel Palliative Care models are needed to met needs to improve care of HF pts JACC Journals #JACCHF

New in #jacchf 
⭐️Role of Palliative Care Across HF

Improves
⬆️ Sx Control
⬆️ QOL
⬆️ Caregiver satisfaction
⬇️ Caregiver Anxiety.

🔑 Limited Palliative care workforce
✅ Novel Palliative Care models are needed to met needs to improve care of HF pts <a href="/JACCJournals/">JACC Journals</a>  #JACCHF
Novi Tham (@slumberbell) 's Twitter Profile Photo

How to define #PreHF stage⁉️ Dr #AntoniBayesGenis and BiykemBozkurt proposed 3 categories to define this grey area: 1️⃣Structural Heart Abnormalities -🫀structural/functional issue w/o ⬆️ NPs - e.g: LVH, chambers enlargements, wall motion abnormalities 2️⃣Heart Stress -⬆️#Biomarkers

How to define #PreHF stage⁉️

Dr #AntoniBayesGenis and <a href="/BiykemB/">BiykemBozkurt</a> proposed 3 categories to define this grey 
area:

1️⃣Structural Heart Abnormalities
-🫀structural/functional issue w/o ⬆️ NPs
- e.g: LVH, chambers enlargements, wall motion abnormalities

2️⃣Heart Stress
-⬆️#Biomarkers
Jenny Thibodeau, MD, MSCS (@jtthibs) 's Twitter Profile Photo

#GDMTworks, but we still aren't using it. New in #JACCHF: in 40K pts w newly dx #HFrEF, slow uptake on GDMT initiation w disparity btwn rural & urban use. 16% excess mortality risk for rural pts. *We can do better* 👀:jacc.org/doi/10.1016/j.… JACC Journals Gregg Fonarow MD ambarish

#GDMTworks, but we still aren't using it. New in #JACCHF: in 40K pts w newly dx #HFrEF, slow uptake on GDMT initiation w disparity btwn rural &amp; urban use. 16% excess mortality risk for rural pts. *We can do better*

👀:jacc.org/doi/10.1016/j.…

<a href="/JACCJournals/">JACC Journals</a> <a href="/gcfmd/">Gregg Fonarow MD</a> <a href="/ambarish4786/">ambarish</a>
Alnylam Pharmaceuticals (@alnylam) 's Twitter Profile Photo

We are pleased to share positive topline results from our HELIOS-B Phase 3 study of vutrisiran, an investigational #RNAi therapeutic in development for the treatment of #ATTR #amyloidosis w/ cardiomyopathy. Read the press release: bit.ly/3VwvRtY #RNAiTherapeutics #siRNA

BiykemBozkurt (@biykemb) 's Twitter Profile Photo

CLOROTIC Trial: Adding HCTZ to IV furosemide seems to be an effective strategy for improving diuretic response in AHF across the spectrum of EF: similarly in HFrEF, HFmrEF and HFpEF. in #JACCHF jacc.org/doi/10.1016/j.… JACC Journals Marta Sánchez Joan Carles Trullàs, MD, PhD

CLOROTIC Trial: Adding HCTZ to IV furosemide seems to be an effective strategy for improving diuretic response in AHF across the spectrum of EF: similarly in HFrEF, HFmrEF and HFpEF. in #JACCHF jacc.org/doi/10.1016/j.… <a href="/JACCJournals/">JACC Journals</a> <a href="/msanchezmar/">Marta Sánchez</a> <a href="/jc_trullas/">Joan Carles Trullàs, MD, PhD</a>
Jenny Thibodeau, MD, MSCS (@jtthibs) 's Twitter Profile Photo

New review in #JACCHF by Kieran Docherty on the treatment and prevention of HF following AMI. * Review of current evidence and guideline recommendations * Discussion of ongoing research * Proposal to identify highest risk pts to guide tx 🔥Don't miss!! jacc.org/doi/10.1016/j.…

New review in #JACCHF by <a href="/Kieranfdocherty/">Kieran Docherty</a> on the treatment and prevention of HF following AMI. 
* Review of current evidence and guideline recommendations
* Discussion of ongoing research
* Proposal to identify highest risk pts to guide tx 
🔥Don't miss!! 
jacc.org/doi/10.1016/j.…
Munir S Janmohamed MD FACC, FHFSA (@munirjanmohamed) 's Twitter Profile Photo

New 📄 in JACC Journals #JACCHF ❓Objective: Compare Health Care QOL (HFQOL) in HF vs Cancer 🫀 Methods: Analysis Medicare 2016-2000 🎯Conclusions: People with HF ⬇️ HFQOL than those with Cancer actively receiving tx. Read More 👇🏼 📎 jacc.org/doi/abs/10.101…

New 📄 in <a href="/JACCJournals/">JACC Journals</a> #JACCHF 

❓Objective: Compare Health Care QOL (HFQOL) in HF vs Cancer 
🫀 Methods: Analysis Medicare 2016-2000

🎯Conclusions: 

People with HF ⬇️ HFQOL than those with Cancer actively receiving tx.  

Read More 👇🏼

📎 jacc.org/doi/abs/10.101…
Henry Han (@hancardiomd) 's Twitter Profile Photo

This combined data from #TRITON & #REPAIR studies (N=148) on initial macitentan + tadalafil therapy shows; 📍#PVR reduction: -55% (no comorbidities) & -50% (1-2 comorbidities) at Week 26 📍Functional improvements observed, lesser extent in comorbid patients 📍Majority improved

This combined data from #TRITON &amp; #REPAIR studies (N=148) on initial macitentan + tadalafil therapy shows;

📍#PVR reduction: -55% (no comorbidities) &amp; -50% (1-2 comorbidities) at Week 26

📍Functional improvements observed, lesser extent in comorbid patients

📍Majority improved
Gregg Fonarow MD (@gcfmd) 's Twitter Profile Photo

In HFrEF, lack of therapeutic urgency is: 🌎 Common 💵 Costly ☠️ Deadly Published in Circulation, 5 core "take-home" principles for rapid & intensive #GDMT as a foundational approach doi.org/10.1161/CIRCUL… Steve Greene Javed Butler

In HFrEF, lack of therapeutic urgency is:

🌎 Common
💵 Costly
☠️ Deadly

Published in <a href="/CircAHA/">Circulation</a>, 5 core "take-home" principles for rapid &amp; intensive #GDMT as a foundational approach

doi.org/10.1161/CIRCUL…

<a href="/SJGreene_md/">Steve Greene</a> <a href="/JavedButler1/">Javed Butler</a>
Munir S Janmohamed MD FACC, FHFSA (@munirjanmohamed) 's Twitter Profile Photo

New in #JACCHF: 🔥 Obesity & Weight Loss Strategies for Patients with Heart Failure Nice review of this important target in the management of #HF JACC Journals JACC HF: jacc.org/doi/10.1016/j.…

New in #JACCHF: 🔥

Obesity &amp; Weight Loss Strategies for Patients with Heart Failure 

Nice review of this important target in the management of #HF <a href="/JACCJournals/">JACC Journals</a> 

JACC HF: jacc.org/doi/10.1016/j.…
Anju Bhardwaj MD FACC (@docbhardwaj) 's Twitter Profile Photo

🔥🔥 ☠️ for phenotypes along preshock -> CS continuum 👉 jacc.org/doi/full/10.10… JACC Journals #JACCHF Critical Care Cardiology Trials Network 🎯 Hypoperfusion +/- hypotension -> ⬆️☠️ 🎯 normotensive CS -> distinct CS phenotype 🎯 Identify pre-& early shock to improve #CardiogenicShock outcomes

🔥🔥 ☠️ for phenotypes along preshock -&gt; CS continuum

👉 jacc.org/doi/full/10.10…

<a href="/JACCJournals/">JACC Journals</a> #JACCHF <a href="/CCCTNetwork/">Critical Care Cardiology Trials Network</a> 

🎯 Hypoperfusion +/- hypotension -&gt; ⬆️☠️
🎯 normotensive CS -&gt;  distinct CS phenotype
🎯 Identify pre-&amp; early shock to improve #CardiogenicShock outcomes