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I am very excited to read this new preprint from Sonja-Verena Albers !! biorxiv.org/content/10.110…

This is super cool —the flip side of previous studies that identified polymerizing metabolic enzymes by screening collections of GFP-tagged proteins

High-speed capture of blood flow in a larval zebrafish. Credit to Julien Rességuier 🇪🇺 🇫🇷 🇳🇴. #ZebrafishZunday

Cool! Choano calcium signaling

#FluorescenceFriday #cellbiology #bioart A neutrophilic HL-60 cell exhibits both sheet- and rosette-like dynamic pseudopods as it migrates in 3D through a collagen mesh. Here, the cell center is marked in yellow, and each pseudopod is marked with an orange ball of size

I don't know which specific post or storm this is responding to, but as a statement of general principle, I couldn't agree more.

Superstar inaugural Manor Lab postdoc Cara's new paper is up! Here we show ER-actin accumulates at ER-organelle contacts to regulate their fission and mobility. This applies to mitos, lysos, and endosomes, and is mediated by INF2, an ER-anchored formin. biorxiv.org/content/10.110…

#newPI I'm here to talk about methane-producing archaea! Marine Biological Laboratory (MBL)

“I am here to chew bubble gum and talk about methanogens… and I’m all out of bubble gum”

Archaeal Cell Biology working group 2024 The Real Mullins Lab Dyche Mullins et al. @A_CharlesOrszag

Huge congratulations to Lil Fritz-Laylin!

Thrilled to announce the Lawrence Lab will open its doors within UCLA Biological Chemistry UCLA Biological Chemistry in January 2025! I couldn’t be more excited!

Visualizing moth wing scale development with Kyle A DeMarr from Dyche Mullins et al. on Alfred Millett-Sikking's AIRR snoutscope today! Using a 1.3 oil-immersion lens to image >100 um deep past the moth's cuticle. Absolutely gorgeous biology and microscopy.

Congratulations to CMP Assistant Professor Jeannette Tenthorey (Jeannette Tenthorey) for receiving the NIH Director's New Innovator (DP2) Award! UC San Francisco UCSF School of Medicine UCSF CMP

Hmm. Food for thought

Two-chambered heart of a live zebrafish embryo. Credit to Rashmi Priya. #ZebrafishZunday

New study out on bioRxiv! We have studied how resources are shared between actin networks competing for a limited pool of components. biorxiv.org/content/10.110…

The high point of any graduate program retreat has to be the Booth-Buchwalter cocktail party. Young faculty like this give me hope for the future. David Booth @abbybuch

Lovely analysis by Dyche Mullins et al. of a somehow underrated effect: Membrane tethering reduces molecular diffusion from 3D to 2D, which can accelerate local actin polymerization. Super important when contemplating 3D in vitro metrics in cellular context! biorxiv.org/content/10.110…

Membrane-associated polymerases deliver most of the actin subunits to a lamellipodial network biorxiv.org/content/10.110… #biorxiv_cellbio