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'Bridging scales' from #smallmolecules to #cells. How can we combat the development of #humandiseases like #cancer? Max Planck Institute of Molecular Physiology
ID: 715154545475772416
http://www.mpi-dortmund.mpg.de/imprint 30-03-2016 12:31:45
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This Stefan Raunser review summarizes recent insights into the molecular mechanisms of #actin polymerization and disassembly obtained through high-resolution structures of actin filament assemblies. #cryoEM ➡️sciencedirect.com/science/articl…

High-level teamwork for a better molecular understanding of muscle wasting - Structural biologist and Humboldt-Stiftung Fellow Alexey Amunts will be researching age-related bioenergetics together with MPI Director Stefan Raunser ➡️mpi-dortmund.mpg.de/news/2025/high…




A molecular syringe paves the way to new therapeutic approaches - read how a team of researchers @intein Max Planck Society Université de Genève BordignonLab & University Düsseldorf found important insights into how pathogenic bacteria inject deadly enzymes ➡️mpi-dortmund.mpg.de/news/molecular…



Huge congrats to Heng Zhou & Jagannath Maharana @the_rajem on being awarded the prestigious Humboldt Humboldt-Stiftung Fellowship! Jagannath will investigate the causes of inherited cardiomyophaties & Heng how certain bacterial Tc toxins target and enter host cells #cryoEM #cryoET


Paper Alert🚨 Interactions with multiple inner kinetochore proteins determine mitotic localization of FACT - published by the Musacchio Group in Journal of Cell Biology ➡️rupress.org/jcb/article/22…

Interactions with multiple inner #kinetochore proteins determine mitotic localization of FACT, say Julia Schweighofer, Bhagyashree Mulay, Andrea Musacchio and colleagues MPI Dortmund: hubs.la/Q03c4Rjw0 #Mitosis



🚨Paper alert🚨 The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning - Published in The EMBO Journal by the Peter Bieling Group & Bement Lab & Scott Hansen Group embopress.org/doi/full/10.10…

We congratulate Max Haase, #Postdoc in the lab of Andrea Musacchio, on receiving the highly-coveted Marie Skłodowska-Curie Actions Postdoctoral Fellowship funded by the European Commission


An Indole Dearomatization Strategy for the Synthesis of Pseudo-Natural Products - New publication by the Waldmann Group published in ChemBioChem …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

New Parkinson’s disease paper: Chimeric deubiquitinase engineering reveals structural basis for specific inhibition of USP30 and a framework for DUB ligandability - published by Malte Gersch group Max Planck Society in nature Struct. & Mol. Biol. nature.com/articles/s4159…

There are currently high hopes for the development of novel Parkinson's drugs. Malte Gersch group has now deciphered the mode of action of these drugs. The findings can help to develop innovative therapeutics for #Parkinsonsdisease & other disorders. mpi-dortmund.mpg.de/news/promising…


In a twin study, researchers MPI for Biological Intelligence successfully characterized gut bacteria involved in #MultipleSclerosis and provided evidence of their pathogenicity. mpg.de/24685137/0507-…

With great sadness and deep regret, we have to inform you that our department director and highly esteemed colleague Philippe Bastiaens Max Planck Society passed away suddenly and unexpectedly on 15th of May.



🚨Paper alert🚨 Interplay of kinetochores and catalysts drives rapid assembly of the mitotic checkpoint complex - published by the Musacchio Group Max Planck Society in Nature Communications nature.com/articles/s4146…