Great talk by Hannah Uckelmann from Goethe-Universität at #EHA2024, providing a comprehensive vision of the future of truly targeted therapies in AML.

Interesting work by Hao Zhu Lab on role of #oncofetal regulon LIN28 in Liver cancer initiation #JCI jci.org/articles/view/…

MYC-stery of Down syndrome unraveled ow.ly/IWIi50SmJc9 #myeloidneoplasia

Congratulations, Henning! Very well-deserved!

Cooperativity of #pioneerfactor FOXA1 with co-factors. Are TFs the real masters of #epigenetics? FOXA1 binding appears to be largely independent of #chromatin context. What does this mean for the classical definition of #epigenetics, which is DNA sequence-independent?

Excited about multi-omics in health? We have a fully-funded PhD position on AI for multi-omics analytics as part of HIDDS4Health call 2024. Apply here: hidss4health.de

Exciting preprint from Lars Velten and Robert Frömel et al. discovering negative synergies of transcription factors as a mechanism of cell type-specificity on enhancers. Unanticipated findings made possible by use of thousands of synthetic enhancers.

Every year, 400,000 children are diagnosed with cancer, many without access to proper care. A tough journey affects their health, emotions, and future. Let’s support Childhood Cancer Awareness Month and stand with the most vulnerable. #CCAM @ACCOrg Hopp-Kindertumorzentrum Heidelberg (KiTZ) DKFZ Universitätsklinikum Heidelberg

I'm excited to share our preprint "Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q": doi.org/10.1101/2024.0…. This is my main PhD work and a massive collaborative effort. 🧵👇

Excellent chemistry meme. I hope it goes chiral!