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Targeted protein degradation: a promise for undruggable proteins #PROTAC cell.com/cell-chemical-…

Hello everyone! I’m Giulia Iannelli, a PhD student at EpigeneticMedChemLab Università Salerno My poster (PC_28) is focused on design, synthesis, biological evaluation and binding studies of new sub-nanomolar inhibitors of CARM1 (PRMT4). Net4Science #PEVM2021 #medchem

I'm Giuliana Sarno, a PhD student at EpigeneticMedChemLab Università Salerno. My poster (PC_60) is focused on development and application of a biophysical platform for the identification of fragments for the development of SETD8 ligands. Net4Science #PEVM2021 #medchem

A state-of-the-art review on lysine methyltransferase inhibitors by EpigeneticMedChemLab just published in RSC Chemical Biology pubs.rsc.org/en/content/art…. Monica Viviano AlessandraFeoli Alessandra Cipriano Ciro Milite Sabrina Castellano

The final version is out as advance article in an #OpenAccess #TransparentPeerReview format. EpigeneticMedChemLab Monica Viviano AlessandraFeoli Ciro Milite Alessandra Cipriano Sabrina Castellano

📢📢Last days for the Postdoc application in our lab 📢📢 Deadline 15.01. olallalab.org/join-the-team/ Please RT. Thanks!

Foto appena pubblicata @ Università degli Studi di Salerno instagram.com/p/CZ2jViHsMet/…

Our work on deconstruction–reconstruction approach turning non-selective type I PRMT inhibitors into potent and selective PRMT4 inhibitors is now available (open access) in ACS Publications Bio & Med Chem Content JMC (asap). Thanks to all coauthors! EpigeneticMedChemLab   shorturl.at/bnuEZ

🚨 GalChimia is hiring!!! Senior R&D Chemist for the Galchimia center in Barcelona. You can find detailed information about it in the following link 👇🏽 🔗 galchimia.com/es/joinus/rese… linkedin.com/feed/update/ur…

If you are interested in Targeted Protein Degradation, this is a great opportunity to be updated on the field!

A very nice collaboration of ⁦EpigeneticMedChemLab⁩ with ⁦Alessio Ciulli⁩ and Panagis Filippakopoulos led to the identification of BET inhibitors with selectivity for the 1st bromodomain. Just accepted in ⁦ChemMedChem⁩. Congrats to all! …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cm…

Only a bunch of our excellent keynotes, oral and flash communications here at #NMMC27 IIT Adam Pecina Monica Viviano 🔥 🔜🔝💯 #medchem

The end of a journey, the beginning of the future. A hug that encompasses everything we shared. A photo that remains a memory of places, facts, words. A thesis as a symbol of an experience that we will keep in our hearts. Ad maiora 🎓♥️

Congratulations to all the members of the EpigeneticMedChemLab team. AlessandraFeoli Giulia Iannelli Alessandra Cipriano Monica Viviano Ciro Milite Giuliana Sarno Sabrina Castellano and to Maria Chiara Monti and Elva Morretta (Università Salerno Dept. of Pharmacy)

Our Perspective on NADPH Oxidases, spanning from molecular mechanisms to current inhibitors has just been published on-line (open access) in J. Med. Chem. (ACS Publications Bio & Med Chem Content). Thanks to all the members of EpigeneticMedChemLab involved! pubs.acs.org/doi/10.1021/ac…

Amazing social dinner at #NMMC28 in Chieti #medchem

NMMC28 is nearing completion, and the #DIFARMA of Università Salerno actively participated in the event. Proud to be part of this wonderful reality! #EMCL #campiglialab

Chemistry is, technically, the study of substances, but I prefer to see it as the study of changes. For example, electrons change their energy levels; molecules change their bonds; elements combine and change into compounds. Well, this is life! And it's fascinating! - W. White

Poster session #2 will start soon at #EFMCISMC24. What a wonderful experience in Rome for EpigeneticMedChemLab ! I’m very happy to present my poster on gold complexes as new TSPO ligands for ovarian cancer treatment. Hope to see you at 654 stand!

The new issue of ChemMedChem is out, with a Front Cover showing a prodrug approach to exploit (S)-alanine amide as arginine mimic moiety in the development of protein arginine methyltransferase 4 inhibitors. …mistry-europe.onlinelibrary.wiley.com/toc/18607187/c…