Super excited that my trainee Leonardo Velazco-Cruz is defending his PhD dissertation next week!

Our strategy for making islets from ES/iPS cells is now out in Nature Protocols. We illustrate making islets from patient iPSCs (T1D, T2D, MODY, Wolfram Syndrome). This is very detailed (35 pages). We hope that this is a useful resource for other labs. nature.com/articles/s4159…

First in human nytimes.com/2021/11/27/hea…

Last month, Vertex announced promising data from its Phase I/II Clinical Trial, that the first person with T1D to receive a stem cell derived therapy, VX-880, required 91% less insulin 90 days (1/4)

This is what hard work and dedication look like! Congrats Punn Augsornworawat 🥳

Very excited to share our new pre-print performing single-cell multiomics to characterize human stem cell-derived islets. New and unexpected insights contained within! WashU Endocrinology, Metabolism & Lipid Research WashU Biomedical Engineering WashU Center of Reg Med @WUSTLdbbs biorxiv.org/content/10.110…

Great collaboration by many people in my lab. Punn Punn Augsornworawat, Erica, Marlie Marlie, Matt Matthew Ishahak, Sarah Sarah Gale, Mason Mason Schmidt, Danny Daniel Veronese Paniagua, Julia, and Leo Leonardo Velazco-Cruz

Check out Marlie's posters right now!

I had a fantastic time yesterday discussing my research on islet stress at ISSCR. Thank you to everyone that came by and Jeffrey Millman for providing me this opportunity (and being the best)!!!#ISSCR2022

First Millman lab #ISSCR2022 presentation today will be by Punn Augsornworawat Punn Augsornworawat , 5th year PhD student in WashU Biomedical Engineering on "Transcriptional regulators of maturation in stem cell-derived beta cells"

The second and third Millman lab #ISSCR2022 presentations today will be at 4p. One will be by Mason Schmidt Mason Schmidt, WashU Center of Reg Med Post-Cacc, on "Comparative analysis of the transcriptional landscape of stem derived islets from different protocols"

The third Millman lab #ISSCR2022 presentation of today will be at 4p by Matt Ishahak Matthew Ishahak, a Rita Levi-Montalcini WashU Center of Reg Med Postdoc, on "Modeling glioblastoma using genetically engineered human stem cell-derived cerebral organoids"

The last Millman lab #ISSCR2022 talk will be an oral presentation today by Daniel Veronese Paniagua, a third year @WUSTLdbbs PhD student, on "Utilizing human stem cell-derived islets as a model to study the role of IFIH1 in islet respond to Coxsackievirus B infection"

Successful large transplant of stem cell-derived islets that needed a whole crew! Mason Schmidt Punn Augsornworawat Marlie

It’s great when you work with people that you can also convince to run a 15K with you. #hotchocolaterun

🧬 Exciting new study out in Nature Communications! We identify cell-type-specific responses in pancreatic islets to stress, shedding light on diabetes progression. It is #OpenAccess for all to download for free! #DiabetesResearch Test Account WUSM Department of Medicine nature.com/articles/s4146…

Check out Marlie Maestas' poster at #ISSCR2024 tomorrow afternoon! She will be presenting on the use of single-cell sequencing and stem cell-derived islets for #diabetes disease modeling. Also, checkout her latest paper! @WUSTLdbbs nature.com/articles/s4146…

Congratulations to Marlie Maestas of Millman Lab on her first time as a first author! She shares that while shadowing a physician assistant, "I realized I wanted to be involved in understanding and creating new medicines for people.” bit.ly/3Su7D2I Jeffrey Millman

Marlie Maestas, a fifth-year grad student Jeffrey Millman Lab WashU Endocrinology, Metabolism & Lipid Research recently published her first first-authorship in Nature Communications The study is titled Identification of unique cell type responses in pancreatic islets to stress. Link to read more> l8r.it/2Sjp

Members of the Millman Lab took a break from their scientific work and participated in the Drink MO Beer Run last Saturday at Creve Coeur Park. The event ended with a festival that included beer from local microbreweries, food, and live music. #GoingOutside