The role of metabolism in shaping enzyme structures over 400 million years | Nature nature.com/articles/s4158…

🚀 Excited to share our latest protocol in Nature Protocols : "scGPT: End-to-end Protocol for Fine-tuned Retinal Cell Type Annotation"! Single-cell RNA-seq is transforming biology, but annotating large-scale, high-resolution data is challenging. Our team introduces a powerful

New publication: Can AI modeling of protein structures distinguish between sensor and helper NLR immune receptors? (2025) tsl.ac.uk/publications/1…

Controlled colonization of the human gut with a genetically engineered microbial therapeutic | Science science.org/doi/10.1126/sc…

Recruitment, rewiring and deep conservation in flowering plant gene regulation nature.com/articles/s4147…

Excited to preprint work mainly by former postdocs Li Feng, Yingnan Hou Yingnan Hou, and the phylogenomics genius AmirAli Toghani The Sainsbury Laboratory. We found a plant defense gene family enabling pathogen gene silencing & explored engineering this pathway to boost disease resistance!

Three back-to-back Salicylic Acid biosynthesis papers 1/3 nature.com/articles/s4158… from Yuelin Zhang’s group (my PhD supervisor)

A human homolog of SIR2 antiphage proteins mediates immunity via the Toll-like receptor pathway | Science science.org/doi/10.1126/sc…

🎉 Our new paper is out in Science Advances! Plants can detect parasitic nematodes. science.org/doi/10.1126/sc… #PlantImmunity #Nematodes #Arabidopsis #Scienchttps://www.science.org/doi/full/10.1126/sciadv.adv8896?af=Re

🎉 Thrilled to share our latest work, now published in New Phytologist! 🌱 Aphid effector Mp10 fine-tunes plant immunity via EDS1, balancing suppression and activation of defence. 🧑‍🔬Matteo Gravino, Sam Mugford @samtmugford.bsky.social, Saskia Hogenhout et al., John Innes Centre, SapienzaFisVe (curated by Pontiggia) #️⃣

Do plants remember their microbial partners?: Trends in Plant Science cell.com/trends/plant-s…

Years of research on the fundamental processes of microbial ecology have led to a new question: How can we engineer these communities? 🛠️ A review by Joy Bergelson and Lucas Henry summarizes these core principles and their application. nature.com/articles/s4156…

Integrated biotechnological and AI innovations for crop improvement. nature.com/articles/s4158…

Potential and challenges for application of microbiomes in agriculture (Charles Copeland , Paul Schulze-Lefert , Ka-Wai Ma) doi.org/10.1093/plcell… #PlantSci ASPB

We’re excited to share our latest work on plant pathogen effector protein evolution bioRxiv. With Sophien Kamoun and Abbas Maqbool. biorxiv.org/content/10.110…

How can we better understand the plant immune system? In my new Cell Host & Microbe piece, I propose “immune cell states” as a framework for uniting molecular and cellular perspectives. cell.com/cell-host-micr…

New paper out in Cell Host & Microbe. Here, I provide my personal view on "Plant-microbe interactions in the context of global change biology" Department of Plant Science One Health Microbiome Center Huck Institutes Penn State College of Agricultural Sciences doi.org/10.1016/j.chom…

Ever imagined running Seurat with natural language and exploring your data step by step? No code This Pantheon-CLI case study shows a full single-cell workflow—normalization, clustering, QC, marker detection, and cell type mapping—all through conversation. youtube.com/watch?v=z407b9…

Linalool-triggered plant-soil feedback drives defense adaptation in dense maize plantings | Science science.org/doi/10.1126/sc…

Mac mini M4 16+256G的现在只需要2679。可以冲吗？