The NIH suddenly decided to terminate its contract with the Director of the National Institute for Neurological Disorders and Stroke. Walter Koroshetz, MD, FAAN. More than half of the institute director roles at NIH are now vacant: aan.com/policy-and-gui…

wealth managers putting your money in an index fund

You can never be wrong if you focus on the fundamentals. Some short-term fluctuations are possible, but in the long term, fundamentals always win. So, keep your focus on what really matters.

Ben Horowitz on why CEOs need to tell the truth: benahorowitz.eth

The FDA is looking for ways to contract innovative startups.

Marc Andreessen on the advantages of beginners: Marc Andreessen 🇺🇸

Yuchen Jin 2026 is the year of the Singularity

If it takes EY 14 days to remove me from marketing communications, I am not surprised AI is taking over the consulting industry.

Looks like the OSS business model is going to suffer: neowin.net/news/tailwind-… Will the software development shift back to closed source?

California’s wealth tax is indeed ridiculous. Take Ilya Sutskever as an example. He has $20B+ worth of OpenAI equity now. Let’s say he owns 1/3 of SSI, worth $10B+. He has to give California 5% x (20+10) = $1.5B. And he cannot pay with OpenAI/SSI equity. He has to pay in cash!

We’re honored to share that the FDA has approved Guardant360® CDx as a companion diagnostic for BRAF V600E–mutant metastatic #ColorectalCancer, helping identify patients who may benefit from BRAFTOVI® (encorafenib)–based treatment. Details: bit.ly/49ODNh8

AlphaGenome is out in @nature today along with model weights! 🧬 📄 Paper: nature.com/articles/s4158… 💻 Weights: github.com/google-deepmin… Getting here wasn’t a straight path. We sat down @googledeepmind to discuss the story behind the model, paper & API: youtu.be/V8lhUqKqzUc

Vibe coding is the new product management. Training and tuning models is the new coding.

If these were arms of a "Novel Rx vs Standard of Care" study in cancer, they'd be landmark best-in-class Instead it's the same Rx regimen just dosed in the morning or afternoon, for mAbs with half-lives of weeks... A few hours different in dosing leads to 60% delta on survival

Today is World Cancer Day: worldcancerday.org Unique stories with a united message.

I use a very specific prompt to push Claude to check its work and do a lot of testing and thinking about perf and refactoring. I find I can do big features (4K LOC+ with full testing) in about an hour.

I am hiring! If you enjoyed our recent publication (nature.com/articles/s4158…) and are interested in all things systems immunology, paediatric oncology and development, please apply below! Working in the wonderful CRUK Cambridge Institute and The Gilbertson Lab cam.ac.uk/jobs/research-…

Humbling 30 year Biotech stats shared by Dan Rasmussen in a recent report: Just over 1,000 biotechs hit $200M mkt cap at some point. Of those, 67% have lost value (had cumulative negative returns), vs 48% for all other US companies. Of these 600+ biotechs, roughly 50% were

Prediction: In the AI age, taste will become even more important. When anyone can make anything, the big differentiator is what you choose to make. paulgraham.com/taste.html

Want to know the craziest part about insurance company Pre Authorization Denials ? The insurance company defines the network of providers the patient can use When they deny care, they are effectively saying "we don't trust the judgement of the doctors we require you to use"