NucleosomeDB - a database of 3D nucleosome structures and their complexes with comparative analysis toolkit biorxiv.org/content/10.110…

Brilliant 🧵 highlighting the key take home messages we learnt from our characterisation of nucleosomes from the divergent eukaryote T.brucei by @GauriDeak

Thanks for the kind words, glad you enjoyed.

We are delighted to establish our new Discovery Research Platform for Hidden Cell Biology The University of Edinburgh and grateful to Wellcome for support. Biological Sciences | University of Edinburgh @WTcell

Here is our latest work in which we explored the relationship between MeCP2, heterochromatin and DNA methylation using live-cell imaging. This is a collaboration with Tom Burdon The Roslin Institute, Thomas Jenuwein MPI of Immunobiology & Epigenetics and Claude Libert VIB. biorxiv.org/content/10.110…

#ProudPI @GauriDeak winning poster prize for her work on trypanosome chromatin #emblchromatin

EMPIAR.org/EMPIAR-11454 contains raw data for the "Structure of the Nucleosome Core Particle from Trypanosoma brucei", published @NAR_Open (doi.org/10.1093/nar/gk…) by the Marcus D Wilson lab The University of Edinburgh. #EMPIAR #cryoEM #NeglectedTropicalDiseases

We are very excited to share with you the results of great teamwork with @AmelieFT lab! In this study, two graduate students Edgar Pinedo-Carpio and @DessaptJcharacterized the critical role of FIRRM/C1orf112 in the disassembly of RAD51 during DNA repair. science.org/doi/full/10.11…

Job Alert📢📢 We are recruiting postdocs in Protein Biochemistry bit.ly/45vrx1A & Cell Biology bit.ly/45ijcOX to join our lab Department of Biochemistry at Oxford University. Join us to tackle the next big challenges in the Wnt signalling field in a fun, collaborative & supportive environment!

Our 10 week virtual course on the theory of cryo-EM returns again next month. Full details and registration: gla.ac.uk/research/az/cv… (NB. open to consortium member universities only)

Join us for the first Scottish Symposium on Cryo-electron Microscopy !❄️🔬🏴󠁧󠁢󠁳󠁣󠁴󠁿eventbrite.co.uk/e/scottish-cry… SCMI UoD Life Sciences Centre for Targeted Protein Degradation SULSA co-organised with Mark A. Nakasone Tom Owen-Hughes Charlotte Crowe

BRCA1–BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes academic.oup.com/nar/article/do…

Great talk by Hannah Wapenaar from Marcus D Wilson lab solving some beautiful structures and highlighting tips and tricks from data processing software packages for #cryoEM #Scottish_cryoEM23

The paper version of our DNMT3B study is now out in EMBO Reports 🥳: embopress.org/doi/full/10.10… You can read more on the previous thread but here is a summary of the main updates. This is one for Southern blot fans! 🧵1/9

Wonderful collaboration, really excited to see the final version out.