Shane McCarthy
@mcshane
Assembler of genomes for the Tree of Life programme at Wellcome Sanger. Ex-physicist. Sandgroper
ID:952411
11-03-2007 20:20:25
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712 Followers
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Excited to announce our new review: Beyond the Human Genome Project: The Age of Complete Human Genome Sequences and Pangenome References. w/ Benedict Paten Rajiv McCoy Karen Miga Eimear Kenny et al. annualreviews.org/content/journa…
Interesting #AssemblyCuration today Wellcome Sanger Tree of Life Programme. HiC-phased diploid assembly of a dragonfly. Curating both haplotypes together in a merged map. Pics show X and Y sex chromosomes that were mashed up between the haps and also lots of false duplication by hifiasm to be removed.
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In this preprint, Aylwyn Scally, Richard Durbin and I present evidence for deep population structure shared by all modern humans biorxiv.org/content/10.110… Aylwyn Scally Richard Durbin
Delighted this is out, led by Brice Letcher , culmination of 10 yrs of work,started by Sorina Maciuca. New genome graph methods took a lot of work, but paid off, and Brice showed gene conversion between genes explained unusually deeply diverged lineages in 2 surface antigen genes.
I worked in Shane's team for 4 years. They were some of the best years of my life. One of the positions is to replace me. Our DToL project is wonderful. I'm still in the project, just in another position now. Apply today! Darwin Tree of Life
This is an amazing opportunity to be part of the world leading genome generating engine! Join us at Wellcome Sanger Tree of Life Programme
The complete sequence of a human Y chromosome biorxiv.org/cgi/content/sh… #biorxiv_genomic
I've been dying to tell you all! I'm going on a national tour in 2023 representing the Australian Institute of Physics Australian Institute of Physics Looking forward to meeting lots of people as the Women in Physics lecturer.
aip.org.au/News/13010152
Read our #DarwinTreeOfLife article for NatureEcoEvo, where we ask 'Does #genome size matter?'
For our scientists, trying to work out resources needed for each species, the answer is a resounding 'yes!'
Find out more: ow.ly/9frb50Luabw
Kew Science Cibele Sotero-Caio Shane McCarthy
Last day to apply for these roles with the Wellcome Sanger Tree of Life Programme Assembly Team!
Looking for genome assembly innovator to tackle hard problems arising in sequencing 1000s of species. jobs.sanger.ac.uk/vacancy/princi… #DarwinTreeOfLife