Matteo Mazzocca (@mazzocca_matteo) 's Twitter Profile
Matteo Mazzocca

@mazzocca_matteo

Postdoc @hansen_lab | 3D genome and gene regulation

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calendar_today12-10-2022 20:34:47

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@mazzocca_matteo

4 months ago

3/ We ran simulations to estimate EP search times based on 1) measured subdiffusion, 2) physical/genomic distance. Within 300nm (~<200 kb), a gene can find 1000s of enhancers in minutes. Such encounters can’t be selective → EP selectivity needs other mechanisms, e.g. biochemical

3/ We ran simulations to estimate EP search times based on 1) measured subdiffusion, 2) physical/genomic distance. Within 300nm (~&lt;200 kb), a gene can find 1000s of enhancers in minutes. Such encounters can’t be selective → EP selectivity needs other mechanisms, e.g. biochemical