What was the N50?

Have any Genome Browser questions? Come see us at #ASHG2023! Get a sneak peek of upcoming features :)

I’m at @czisinglecell2023 if you’re interested in UCSC Cell Browser let me know

Just to keep things into perspective, we just heard from the daycare for the twins, with Yale support. And it is the entirety of my spouse’s paycheck. Something’s gotta give folks, something’s gotta give.

What do you think this is and what would you do?

We have just updated our default genome locations for hg19/hg38 from POMC to the SHH gene. While the name Sonic hedgehog may remind us of our favorite blue speedster, the gene plays a key role in embryonic morphogenesis. Explore this new gene: genome.ucsc.edu/s/Lou/newDefau…

We are proud to announce a new hg38 track group consisting of Human Pangenome Reference Consortium data. In this first release, there are tracks displaying features and variations of HPRC results compared to hg38, as well as alignment tracks. See the full announcement: bit.ly/HPRCdataInUCSC…

Excited to announce that I'm looking for industry partners for my new AI venture, CancerGPT. My algorithm has proven >90% accuracy. You just plug in the chemical description for your new drug, ask it to predict whether it will work in human trials, and CancerGPT says "No."

Exploring Transcription factor Binding with UCSC Genome Browser youtube.com/watch?v=gguXc8…

Amazing opening plenary talk at London Calling 2024 #nanoporeconf by my UCSC RNA Center colleague & The Nobel Prize Laureate Carol Greider UC Santa Cruz Science on using Oxford Nanopore sequencing to reveal conservation of chromosome end-specific telomere lengths!

After finishing this book, I can say that I was completely wrong. It’s brilliantly written, well-balanced, and informative. I even came up with a genetic screen idea after reading it 😃 Could be summed up in this quote:

Got milk virus genomes?  (or any H5N1?)  Throw them at usher.bio and see where they land in per-segment trees of tens of thousands of public Influenza A H5N1 sequences!

Check out the latest from Yatish Turakhia! Impressive lossless compression and representation of evolutionary histories using phylogenetic pangenomes.

What I don't get about academia is the chronic lack of celebration. It is hard to get & maintain grant funding, hard to get papers accepted without Faustian bargains, hard to be a great mentor, & hard to maximize trainee success. All of it is hard. We should celebrate everything.

We are excited to introduce the new Item Details feature which simplifies the user experience by displaying track item details in a pop-up dialogue box. More information is available at genome.ucsc.edu/goldenPath/new…

This feature allows the information to be viewed without the need to navigate away from the current page.

There's an epidemic of loneliness in science: Most Scientists move around & usually end up living far from friends they made in their youth. When they settle in a permanent place they're older & have busy lives/careers. All this means many scientists don't have a lot of friends.

Is your first thought also “heart development” and “TFBS!” when you see this ? #gata #tfbs #promoter #encode

i miss my parents ↓ i go home ↓ three days ‘visitor’ treatment ↓ clashes begin ↓ everything becomes a fight ↓ realise why i wanted to leave the place ↓ i leave home ↓ carefree days ↓ i miss my parents

Inspired by @caseybergman, I've removed journal names from HubMed search results (showing MeSH headings instead, when they exist)