Sharing our latest work Journal of Experimental Medicine! We've uncovered that P2RX7 regulates unconventional T cells selectively, particularly subsets that co-produce IFN-γ & IL-4. Hoping this helps more discoveries in the role of these innate-like cells, using inhibitors from the P2RX7/ARTC2 field!

Thrilled to share the results of our 8-year-long expedition into the Wild, the city of #NYC , the wild west of #LosAngelesCA , and more—in search of the roots of gut fungal commensalism! 🧵nature.com/articles/s4158…

Thrilled we were part of #KSTCells25 @KeystoneSymposia in Vancouver 🇨🇦 and reunited with T cell friends & colleagues! Huge thanks to co-organizers Amanda Lund Lab, Nik Joshi & Delgoffe Lab. We can’t wait for the next one!!

Happy to share our recent work led by postdoc Dan Corral showing that the maternal adapative immune system promotes optimal lactogenesis. cell.com/cell/abstract/…

Our latest study, led by Susan Christo, shows CD47 × PD-L1 bispecific antibodies enhance tumor-resident CD8+ T cell responses, boosting anti-tumor immunity. Grateful to partner with Pfizer Oncology Medical to advance cancer research! 🔬 Doherty Institute onlinelibrary.wiley.com/doi/full/10.10…

Our paper introducing Cecelia: a multifunctional image analysis toolbox is now online! check it out Nature Communications nature.com/articles/s4146…

I am saying goodbye as an active member of X (but find me in sandra rodriguez.bsky.social) with our exciting new paper nature. The fruit of massive work by Tommaso Vicanolo, Alaz and Jackson Li, and our superb collaborators Lai Guan NG and stefan uderhardt 🔬🧫💉📷. True teamwork! nature.com/articles/s4158…

Online now: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis dlvr.it/TK8Vkp

A fun collaboration with Dan Kaplan - Check out our latest review on all things skin-immunity out now in Nature Immunology 🔗👇 nature.com/articles/s4159… Pirooz Zareie Doherty Institute

A triumph of perseverance from twitterless Tom Weber, Christine Biben and the team, our in vivo barcoding "LoxCode mouse" used to resolve epiblast fate to fetal organs is finally published in Cell and available to import through The Jackson Laboratory sciencedirect.com/science/articl…

Online now: Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment dlvr.it/TL09jV

Our new study showing that resident memory T cell formation and phenotype varies across the length of the gut: sciencedirect.com/science/articl… Mucosal Immunology with Mackay Lab Maximilien Evrard University of Melbourne Doherty Institute

Online now: A fungal-derived adjuvant amplifies the antitumoral potency of Bacillus Calmette-Guérin via reprogramming granulopoiesis dlvr.it/TLWTv1

Memory T cell formation and phenotype varies across intestinal compartments: mucosalimmunology.org/article/S1933-…

The wait is over, it’s back! 🧪 Granulocyte Meeting 2025 | 15–18 Sept | Shanghai. Big science. Big names. Big City. Don’t miss it. 🔗 g-meeting.org #Gmeeting2025 #Granulocytes #ThePowerOfMany

Delighted to share our new approach to enhance CAR T cell function in solid tumours published today nature. In this work we identify a new strategy to generate armoured CAR T cells. nature.com/articles/s4158…

Excited to share that my PhD work is out in nature today! We engineered armoured CAR T cells to express therapeutic payloads only at the tumour site, to improve their safety and efficacy for the treatment of solid cancers. 1/14 nature.com/articles/s4158…

I’m happy to share our latest work on tumour necrosis! During my time in the Mikala Egeblad lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13) nature.com/articles/s4158…

Hot off the press in@ImmunityCP! 🔥 Proud to share our new perspective — a collaborative effort with fantastic colleagues — proposing a unified framework to classify neutrophil subpopulations. #ThePowerOfMany 👉tinyurl.com/ye22e9fx

📢 Open Positions 📢 We're hiring motivated PhDs & Postdocs to join a cutting-edge research program VIB UGent 🔬in vivo CRISPR screens 💻Multi-omics, Modelling & Deep Learning 🧬Macrophages, Liver homeostasis, Regeneration & Metastasis 💶ERC AdG, FWO & Cancer Grant