Glad to see this out indeed! we demonstrated how ML methods are accurate in modelling antibody structures (especially when considering an ensemble) and then used them in a fast #HADDOCK docking protocol: even when sampling few tens of solutions we get a good model of the complex!

Happy the announce the publication of the ARCTIC-3D software, a tool to perform data mining and clustering of existing structural interface information coming from Protein Data Bank code available at github.com/haddocking/arc… web server: wenmr.science.uu.nl/arctic3d/

Our Arctic3D software is now available on #pypi allowing for simple local installation pypi.org/project/arctic…

Happy to announce that our #HADDOCK team did very well in the CAPRI round 56, with a medium quality model of the difficult peptide-MHC-antibody complex submitted as top ranked prediction. Full story at capri-docking.org//assessment/

Long overdue and finally available our BioExcel CoE EGI Faculty of Science, Utrecht University HADDOCK2.4 server paper - freely viewable online at rdcu.be/dK4Hr

All-atom vs. coarse grained

🧬 Exciting news! Our latest preprint is out: a deep dive into the fascinating world of protein-glycan interactions!

Towards the accurate modelling of antibody-antigen complexes from sequence using machine learning and information-driven docking 1/ This study develops a protocol that combines machine learning (ML) with information-driven docking to model antibody-antigen complexes from

Followed by a #HADDOCK protein-glycan modelling paper - doi.org/10.1021/acs.jc…

Excited to share the latest #HADDOCK developments at the BioExcel CoE conference, with some of the brightest minds in the field 🧬 amazing science and great atmosphere here in Brno!

#Bologna5🚕❤️🏅

Modeling Protein–Glycan Interactions with HADDOCK #Docking pubs.acs.org/doi/10.1021/ac… Marco Giulini Alexandre Bonvin - also on Bluesky #JCIM Vol64 Issue19 #Bioinformatics

Interested in #antibody modelling? Marco Giulini will discuss the current state of antibody modelling in the post-AlphaFold era in our next webinar: 🗓️ 8 April 2025 (15:00 CET) ✍️ bit.ly/4bYUozP #HADDOCK #AlphaFold #proteindesign #compchem

Our webinar "Modelling antibodies in the post-Alphafold era: where are we now?" is next week on Tuesday 8 April at 15:00 CET Don't forget to register ➡️ bit.ly/4bYUozP #antibody #HADDOCK #AlphaFold #proteindesign #compchem

1) Comune per comune, spiaggia per spiaggia, il 50% deve essere sempre libero; 2) del restante 50%, il 20% attrezzato dai comuni, il 30% a bando; 3) sulle spiagge non deve rimanere alcuna struttura fra ottobre e aprile; 4) le concessioni non possono superare i 10 anni.