Metabolism is known to affect developmental tempo. In this preprint, we explore the role of different metabolic inhibitors on the segmentation clock biochemical parameters. Overall, we found that metabolism does not act as a global modulator of tempo.

Sound localization by fish was long considered physically impossible, until it was shown behaviorally. How do they do it? Johannes Veith, Thomas Chaigne and team dove into this question with Danionella cerebrum. nature.com/articles/s4158… [1/11]

Here are some neural fireworks for 4th of July! A 3D reconstruction of a pair of optogenetically triggered spikes in a CA1 pyramidal cell, acute slice. Stim to blue branch. With Liam Paninski's lab, supported by CZI Science. biorxiv.org/content/10.110…

The newest research from IPN Director Olson Lab and team suggests that tropane analogs can promote #neuroplasticity with fewer side effects than compounds like scopolamine. Read more here: pubs.acs.org/doi/10.1021/ac…

Are you ready to question your beliefs about hippocampus and cortex? See Jieyu Zheng and Rogério Guimarães at #CCN2024.

science.org/doi/10.1126/sc… very interesting study! Would be cool to check if there are any other areas in which activity/NMDAR expression is more similar to LHb apart from the hippocampus

New paper from the lab published in Nature Communications today: nature.com/articles/s4146… led by first author Luis M. Franco Brief recap of the findings in the thread below:

Very interesting - I wonder how this compares to the effect the DXM/bupropion combo has on the NE/DA/5-HT systems. And also the effect both have on astrocytes!

Astrocyte Gi-GPCR signaling corrects compulsive-like grooming and anxiety-related behaviors in Sapap3 knockout mice: Neuron cell.com/neuron/fulltex… Congrats to Joselyn, Chiran and the whole team on this one!

Super cool paper! Specially the fact that Gi, but not Gq, manipulation had an effect and improved both morphology and behavior. Also "hM4Di activation was comparable to fluoxetine"! Excited for future astrocyte-focused treatments to come cell.com/neuron/fulltex…

Congrats! One of many awards to come I'm sure 😎Jorge Lázaro

Olúmídé Fagboyegun: A neuroscience rising star - Boston Children's Answers Wonderful profile on the talented ⁦Olúmídé Fagboyegun⁩ —one of the 2024 ⁦HHMI NEWS⁩ Gilliam Fellows answers.childrenshospital.org/olumide-fagboy…

“Ketamine’s place within the psychoactive pharmacopeia is perpetually controversial, perhaps because it exposes the fault lines in a premise of modern psychopharmacology, namely, that a drug response…occurs through the action at individual receptors.” psychiatryonline.org/doi/10.1176/ap…

Check this out 🧠 New paper from the lab 🥳 Serotonin release in the habenula during emotional contagion promotes resilience | Science ⁦Manuel Mameli⁩ ⁦Department of Fundamental Neurosciences⁩ ⁦Patricia Molina⁩ ⁦Mauro Congiu⁩ ⁦⁦Leo Michel⁩ science.org/doi/10.1126/sc…

Cell swelling enhances ligand-driven β-adrenergic signaling nature.com/articles/s4146…

Such a fascinating study on one of the coolest regions in the zebrafish brain- lateral inhibition in the habenula through mGluRIII! Amazing to see findings conserved in both fish and mice 🐠🐁 Congrats to all the authors!

PhDone!!! 🤗

Excited to post a new preprint, work by Takashi Kawashima, Ziqiang Wei 魏 子强 and collaborators: Voltage imaging reveals circuit computations in the raphe underlying serotonin-mediated motor vigor learning biorxiv.org/content/10.110…

Rapid physiological integration of fused ctenophores sciencedirect.com/science/articl… Crazy cool 🤯How many ctenophores can we fuse together?