During puberty, testosterone levels surge in males (100-150x), driving muscle growth, voice changes, and facial hair. In females, levels rise slightly (2-5x), but estrogen dominates, shaping different physical changes (even hair texture)

Neural pathways strengthen through more receptors at connection sites (eg AMPA), calcium-based signaling (eg NMDA), growth of neuron branches / myelin sheath, and gene changes that lock in memory. These changes make frequently used pathways stronger and more efficient over time!

Nature gave us a conserve energy function. it’s called sleep.

Can’t erase knowledge from a language model trained prior! #SavingData

Hold it for 8 years… it’s sector value will return ? -Scott Minerd true or nah?

UV light excites electrons in orbital clouds of DNA bases, shifting them to higher energy states. In pyrimidines, this forms dimers, causing mutations like C→T transitions. Purines (A, G) are less reactive to UV. Overexposure disrupts DNA repair, raising melanoma risk.

Arctic fish survive freezing temps using antifreeze proteins (AFPs: Type I-III, AFGPs) that bind to ice crystals, halting growth & creating thermal hysteresis. No intracellular freezing; supercooled fluids stay liquid. Cryo tools

Eavesdropped on a date and it got me thinking about how some chemistries just don’t work, in biotechnology and romance

Do health insurance companies deserve profit?

Who’s building the magneto-reception gene therapy? Add some senses

If behaviour is largely genetic - we should be able to predict mass behaviour among various species too with the same algo?

Certainty may very well be inefficiency

Or must we consider that scale achieves market efficiency (PE owned RE)… ethically contentious, but scale enables systematically reducing costs (at a point in cost schedule decreasing per unit)

I love the fact that keratinocytes produce neurotrophic factors

dCas > Cas

Integrative aging gene network simulation: let’s say using all omics yields ~92% accuracy…. Without epigenetics, accuracy drops to ~82.5%; without proteomics, it’d be ~84.5%. … but let’s say 9-10% is your pentaly if you miss an omic in your simulation.

Solid in vitro proof‐of‐concept, key assay development, pilot delivery system production & optional animal studies to de-risk before raising seed

Self directed revolution vs unconscious drift … which are you living in

Aging puts you predisposed to both hypothermia and heat stroke

Pressure ulcers are wild! Biology gone haywire