f(G)xE (@mantuacordial) 's Twitter Profile
f(G)xE

@mantuacordial

🧬Bio-focused releasing свои thoughts | Is it tech-bio or biotech?

ID: 1647580474410168320

calendar_today16-04-2023 12:40:21

217 Tweet

125 Followers

638 Following

f(G)xE (@mantuacordial) 's Twitter Profile Photo

During puberty, testosterone levels surge in males (100-150x), driving muscle growth, voice changes, and facial hair. In females, levels rise slightly (2-5x), but estrogen dominates, shaping different physical changes (even hair texture)

f(G)xE (@mantuacordial) 's Twitter Profile Photo

Neural pathways strengthen through more receptors at connection sites (eg AMPA), calcium-based signaling (eg NMDA), growth of neuron branches / myelin sheath, and gene changes that lock in memory. These changes make frequently used pathways stronger and more efficient over time!

f(G)xE (@mantuacordial) 's Twitter Profile Photo

UV light excites electrons in orbital clouds of DNA bases, shifting them to higher energy states. In pyrimidines, this forms dimers, causing mutations like C→T transitions. Purines (A, G) are less reactive to UV. Overexposure disrupts DNA repair, raising melanoma risk.

f(G)xE (@mantuacordial) 's Twitter Profile Photo

Arctic fish survive freezing temps using antifreeze proteins (AFPs: Type I-III, AFGPs) that bind to ice crystals, halting growth & creating thermal hysteresis. No intracellular freezing; supercooled fluids stay liquid. Cryo tools

f(G)xE (@mantuacordial) 's Twitter Profile Photo

Eavesdropped on a date and it got me thinking about how some chemistries just don’t work, in biotechnology and romance

f(G)xE (@mantuacordial) 's Twitter Profile Photo

If behaviour is largely genetic - we should be able to predict mass behaviour among various species too with the same algo?

f(G)xE (@mantuacordial) 's Twitter Profile Photo

Or must we consider that scale achieves market efficiency (PE owned RE)… ethically contentious, but scale enables systematically reducing costs (at a point in cost schedule decreasing per unit)

f(G)xE (@mantuacordial) 's Twitter Profile Photo

Integrative aging gene network simulation: let’s say using all omics yields ~92% accuracy…. Without epigenetics, accuracy drops to ~82.5%; without proteomics, it’d be ~84.5%. … but let’s say 9-10% is your pentaly if you miss an omic in your simulation.

f(G)xE (@mantuacordial) 's Twitter Profile Photo

Solid in vitro proof‐of‐concept, key assay development, pilot delivery system production & optional animal studies to de-risk before raising seed