Excited to share this discovery: Huntington's disease is a DNA process for almost all of a cell's life. Inherited HD alleles are innocuous, just unstable – CAG repeats slowy expand throughout life, acquiring toxicity only when quite long (>150 CAGs). biorxiv.org/content/10.110…

That's my buddy! well deserved Erick Armingol 👏

The self supervised single cell model race has clearly begun. Papers focus on architecture engg. boasting bigger models, bigger data, limited & often flawed benchmarks. Please move forward from benchmarking gym & show biological use cases & insights powered by these models.

Exciting opportunity to join a community that thrives on collaboration!

Our lab, in collaboration with partners from Genentech, Sanofi, @gsk, Pfizer Inc., Wellcome Sanger Institute, and EMBL-EBI, has been awarded £2M by Open Targets to generate novel perturbation data across multiple disease models and develop large generative models to facilitate the discovery

Our scverse zulip chat recently crossed 500 members. It's super cool to have so many developers and users in one place to discuss how to best move forward with all things scverse. Please consider joining: scverse.zulipchat.com

Awesome computational methods from my colleague “Charlene” Hsuan-lin Her for modeling protein-RNA interaction data 🤩 and I love the name 👌

So excited to catch up with friends at ISMB in Montreal soon! 🇨🇦 I will be in there from 7/12-7/17, hit me up if you're in town 👋

US citizens or permanent residents from an under-represented group! You can contact any NIH-funded researcher you admire & suggest applying for this supplement to join their lab! High school thru postdoc/faculty. Many, like me, are happy to host! Pls RT grants.nih.gov/grants/guide/p…

Excited to share our work in collaboration with Kevin Corbett on detecting protein-RNA interactions with RNA-base editing in situ in fixed cells and primary tissues. Congratulations Lisa Liang and Tao in our lab! Thank you Chan Zuckerberg Initiative for the support! nature.com/articles/s4146…

I've noticed that biotech cos built around a computational discovery platform have a different philosophy on company building and how to use software to gain sustainable advantage vs. 'traditional' biotech or pharma. I reflect on this in a new blog post: atelfo.github.io/2024/09/17/a-n…

We’re never going there. Creativity is made, not generated. You can read more at procreate.com/ai ✨ #procreate #noaiart