Lum Lab
@lum_lab
Julian Lum's Lab - Autophagy, cancer & immunometabolism. "If you don't fail, you aren't taking enough risks". Views are our own. Tweets by Julian-JJL
ID:1100850819635658752
http://LumLab.ca 27-02-2019 20:11:03
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A dietary commensal microbe enhances antitumor immunity by activating #tumor #macrophages to sequester iron Nature Immunology nature.com/articles/s4159…
Vitamin D appears to promote the immune response to cancer and the success of immunotherapy; now a mechanism is identified involving the gut microbiome interactions
science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
Science Magazine Dr. Kathy McCoy Caetano Reis e Sousa The Crick
Two exciting studies out in nature show that high tumor PGE2 limits IL-2 sensing and antitumor function in TIL. Disrupting this axis can potently enhance antitumor responses. Nice work George Coukos Jan P. Böttcher and teams!
nature.com/articles/s4158…
nature.com/articles/s4158…
Presenting metabolomics analyses: what is in a number? embopress.org/doi/full/10.10…
JMeiser_lab and I wrote this short piece to raise awareness about how present metabolomics data. We hope you will find it useful. Any comment is welcome! thanks Daniel Klimmeck for the support!
A mechanistic insight into how ULK1 regulates the Warburg effect in #BreastCancer .
👨🔬👩🔬
nature.com/articles/s4138…
NEW Review: Cancer cell metabolism and antitumour immunity
bit.ly/3xIIutA
by Mara De Martino Jeff Rathmell Lorenzo Galluzzi Claire Vanpouille-Box
discusses mechanisms by which alterations of cancer cell metabolism interfere with immune functions
Growing evidence shows that dietary interventions can be effective at treating or delaying some diseases, but further trials are needed for wider adoption (especially in cancer)
Nature Medicine
nature.com/articles/s4159…
Self-regulating CAR-T cells modulate cytokine release syndrome in adoptive T-cell therapy. A new study from Meng-Yin Lin, Yvonne Y. Chen and colleagues UCLA Chemical and Biomolecular Engineering Parker Institute for Cancer Immunotherapy: hubs.la/Q02sHNQv0
#TumorImmunology #Immunotherapy
A Review in Nature Rev Immunol reviews the targets, challenges and opportunities for harnessing the anticancer activities of T cells, natural killer cells and myeloid cells with immune cell engagers. 🔒 go.nature.com/480lZNl
Why did the immuno-engineer visit Telsa? 🚗🚗🚗 To develop the Immuno-Tesla, equipped with self-driving CAR-T cells to fight cancers and traffic jams simultaneously! 🙂🙂🙂Complimentary tickets to
🍁 Science World 🍁 available at immunot.ca/news/#DOI 🎫 UBC School of Biomedical Engineering Elon Musk
Don't miss the January 15th @J_immunol special issue: Immunoengineering a Future of Molecular, Material, and Cellular Therapeutics #ReadtheJI #immunology journals.aai.org/collection/348…
So cool for our study to be featured by Pamela Wong and Fehniger Lab in Nature Immunology news & views. They thoughtfully highlight key lines of further study and unanswered questions raised by our work. Thanks Todd!
nature.com/articles/s4159…
The latest paper from our group is now available online as part of Analyst 150th anniversary themed collection “ #Metabolic profiling of murine radiation-induced lung injury with #Raman #spectroscopy and comparative #machinelearning ” ☢️📊
pubs.rsc.org/en/content/art…
Now published Nature Cell Biology📢 Using CRISPRi/a screening, we dive deep into the transporters driving essential nutrient import into cells. Discover more about amino acid transport, metabolism, ferroptosis, and environmental impacts on tumor growth here: rdcu.be/dErUO
Fermented foods have gained popularity owing to their health-promoting potential - this REVIEW discusses the benefits of #fermentedfoods in gut health and disease, and how specific microbes, food components and bioactive compounds exert their effects
rdcu.be/dExvj
