New year, newly released data! This release includes our first PGS for prurigo nodularis (from Chirag Vasavda Dr. Shawn Kwatra Eugene Semenov, MD Sasha Gusev) 👉pgscatalog.org/score/PGS00432…. See pgscatalog.org for all the data, and pgscatalog.org/submit to submit your PGS!

The theme of this week's release is pregnancy, with new PGS for preeclampsia (pgscatalog.org/publication/PG…) and gestational thrombocytopenia (pgscatalog.org/publication/PG…). Thanks to the authors from both papers for sharing the scores!

Excited to share our new preprint describing updates to the PGS Catalog (PGSCatalog.org ) and the PGS Catalog Calulator (pgsc_calc), a new tool for reproducible PGS calculation in the context of genetic ancestry (github.com/PGScatalog/pgs…). Just in time for #ESHG24! /🧵

Some 🌞Summer PGS🌞 data for you in our latest release: - BMI-stratified T2D PGS Takafumi Ojima YukinoriOkada pgscatalog.org/publication/PG… - Multi-ancestry BMI PGS Tinashe Chikowore pgscatalog.org/publication/PG… - Liver cirrhosis pgscatalog.org/publication/PG… ... & more @ pgscatalog.org!

Takafumi Ojima YukinoriOkada Tinashe Chikowore We've also been hard at work on performance improvements to our PGS Catalog calculator software, check out the latest release on our GitHub (github.com/PGScatalog/pgs…) and see our detailed documentation (pgsc-calc.readthedocs.io/en/latest/).

Now available in the PGS Catalog: pgscatalog.org/score/PGS00492… thanks to James Pirruccello et al for submitting! Submit your score pre or post-publication/preprinting, more info at pgscatalog.org/submit.

Last of the summer PGS, new metaPRS in our latest release: - For T2D, including many evaluations from Dr. Scott C. Ritchie @minouye271 et al pgscatalog.org/score/PGS00492… - New PGS for CAD, IS, ICH from China Kadoorie Biobank in Nature Human Behaviour pgscatalog.org/publication/PG… Stay tuned for fall 🍂!

Out today in Nature Genetics! Important new updates to the Polygenic Score (PGS) Catalog, & a new software tool that simplifies the calculation of polygenic scores in the context of genetic ancestry 👉 tinyurl.com/fa5ts5a3 Sam Lambert @minouye271 Dr. Scott C. Ritchie Florent Yvon

📣 New updates to the PGS Catalog. These include multi-ancestry data and a new Calculator to simplify PGS calculations across different ancestries. Learn more about how these updates could enable more equitable disease risk predictions. ebi.ac.uk/about/news/tec…

Huge congratulations to everyone involved! @minouye271 Helen Parkinson Sam Lambert Ben Wingfield, Joel Gibson Laurent Gil Aoife McMahon Laura Harris NHGRI-EBI GWAS Catalog Health Data Research UK (HDR UK) BHF Cardiovascular Epidemiology Unit at Cambridge Baker Institute and more. Read the full Nature Genetics article here 👇 nature.com/articles/s4158…

📢 The Polygenic Score (PGS) Catalog has been updated, including data added from multi-ancestry or non-European populations and a PGS Catalog calculator. The project is a collaborative effort between Cambridge University, EMBL-EBI and NHGRI-EBI GWAS Catalog. Learn more: hubs.li/Q02Rdfc60

Check out the latest developments of all things PGS Catalog, out now in Nature Genetics (🔗: rdcu.be/dVakA )! In this paper we describe big increases in the data content (and diversity) and our tool for PGS calculation (github.com/PGScatalog/pgs…).

>5000 Polygenic scores now available at PGSCatalog.org! As of today's release we've broken 5k PGS, indexing data from 673 unique publications. A big thank you to the authors submitting their data and our team in pursuit of #openscience, #FAIRdata, and reproducibility!

A great day for #FAIRdata and polygenic score research - the PGS Catalog continues to grow past 5000 scores! In honour of the occasion Florent Yvon & I commissioned some AI art (you should see the ones we scrapped). A massive congrats to the whole PGSCatalog.org team!

Interested in software tools for calculating polygenic scores? Sam Lambert & @nebfield are giving an EMBL-EBI Training webinar December 4th about our pgsc_calc tool and it's capabilities for reproducible PGS calculation: ebi.ac.uk/training/event…! Join in or catch the recording after.

🚨We're recruiting! Interested in making science and computing more environmentally friendly? Now is the time! Very excited to build a research group at Cambridge University to expand our Green Algorithms work thanks to the support of the Wellcome green-algorithms.org/join-us/

Polygenic scores can predict an individual’s genetic predisposition to certain traits or diseases. Join our #webinar learn how to use the PGS calculator for calculating polygenic scores. Registration is free but essential: ebi.ac.uk/training/event… #genomics EMBL-EBI PGS Catalog

📣 Thrilled to announce our collaborative tutorial with EMBL-EBI Training! Dive into the world of polygenic scores and explore the PGS Catalog resources (including pgsc_calc) - ideal for those seeking a comprehensive yet quick overview. Access it online at buff.ly/CEBWMio!

Discover data from our latest release: - New PGS for atrial fibrillation (pgscatalog.org/publication/PG…) - PGS optimised for East Asian ancestry in cancer (pgscatalog.org/publication/PG…) and 10 other common diseases (pgscatalog.org/publication/PG…) Submit data at pgscatalog.org/submit

Interested in calculating polygenic scores in the All Of Us workbench? Take a look at our new documentation for how to run pgsc_calc in the cloud environment: pgsc-calc.readthedocs.io/en/latest/how-…. Very much a work-in-progress, optimisations incoming!