Congratulations to our PhD student Pauline Lascaux for being awarded with the French House of Oxford (“Maison Francaise d’Oxford) Gold Medal for her research on the cellular response to chemotherapy. Very proud that our lab continues to produce the top caliber PhD students.

3. Autophagy slows aging by breaking down old proteins and organelles - this paper shows that autophagy also helps to repair DNA This video shows a DNA lesion (in the box) transfer from the nucleus, to the lysosome (blue), for degradation by autophagy cell.com/cell/fulltext/…

An interesting story from Kristijan Ramadan Laboratory NTU Singapore LKCMedicine OxfordOncology TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival cell.com/cell/fulltext/… Interaction between hallmarks of aging (#autophagy, #DNA_repair, #prtoesonal_bio) in

Biggest medical discoveries of the week (🧵) 1/10 Why does caloric restriction boost lifespan? This study of ~1,000 mice finds (surprisingly) it's less to do with lowering fat mass, and more to do with boosting immune function and stress resilience nature.com/articles/s4158…

Noboru shows a 'MD simulation'. ATG9 vesicles move freely due to thermodynamic fluctuations. When they contact the OPTN droplet in the center of the screen, the ATG9 vesicles are captured and anchored to the droplet due to the wetting effect (Mizushima et al. unpublished)

New research by Lascaux et al. highlights how #nucleophagy helps repair toxic DNA lesions. Check our "highlight article" here: nature.com/articles/s4142… And the original paper here: cell.com/cell/fulltext/… #DNARepair #autophagy #ScienceNews

We highlighted and discussed the impressive recent paper of Kristijan Ramadan Laboratory lab on DPCs and selective autophagy: nature.com/articles/s4142… Original paper here: cell.com/cell/pdf/S0092…