Waggoner Lab (@labwaggoner) 's Twitter Profile
Waggoner Lab

@labwaggoner

Research lab of Dr. Stephen Waggoner. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer.
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linkhttps://www.cincinnatichildrens.org/research/divisions/a/genomics-etiology/labs/waggoner calendar_today11-08-2018 22:51:03

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Low doses of MHC-II-restricted neoantigen peptides induce cytotoxic Tr1 CD4 T cells that kill cDC1 and suppress cancer immunotherapy, which can be overcome by LILRB4 blockade, CD8-directed IL-2 mutein, or targeted loss of cDC2/monocytes nature nature.com/articles/s4158…

Low doses of MHC-II-restricted neoantigen peptides induce cytotoxic Tr1 CD4 T cells that kill cDC1 and suppress cancer immunotherapy, which can be overcome by LILRB4 blockade, CD8-directed IL-2 mutein, or targeted loss of cDC2/monocytes <a href="/Nature/">nature</a> 
nature.com/articles/s4158…