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We are recruiting a postdoc! Have expertise in RNA biology and want to apply it to neuro and neurodev disorders? Then apply 👇🏼 📌 $73,588 💰 📌 access to postdoc housing 🏠 📌 Support for internationals 🌍 📌 Awesome view 😅 🙏 RT labs.icahn.mssm.edu/derubeislab/wp…

This is a nice summary of the elegant first paper from Elphege Nora Lab at UCSF lab! Great Job! :D

Corning now offers sterile tips that come in a paper container, thus generating less plastic waste!

🗨️ WANNA TALK TO YOUR CELLS? Try out CellWhisperer – our new multimodal AI that turns single-cell RNA-seq analysis into a conversation. No coding needed, just chat in plain English. Short walkthrough below. Web app & bioRxiv preprint linked in the thread. Let's dive in! (1/9)

1/10🚨 New Findings Alert! 🚨 Discover how genomic heterogeneity and ploidy help predict intrinsic resistance to anti-PD-1 immune checkpoint blockade (ICB) in metastatic melanoma. 🧬science.org/doi/10.1126/sc… 📝 Key takeaways from our latest study: 🧵👇

📢 Paper alert! Our paper on cortical brain organoids multiplexing is out Nature Methods. nature.com/articles/s4159… Together with the Research Briefing nature.com/articles/s4159… /1

Our preprint by Domenic Narducci and the companion preprint by deWitLab are now out in Molecular Cell ZNF143 is not a general looping factor and was identified as such due to a non-specific antibody. Instead it is TF with the longest residence time measured (to our knowledge)

Starting 2025 with a genome architecture paper about absolute quantification of looped states, lead by James Jusuf!

I made a B$sky profile, you can find me here: bsky.app/profile/michel…

Super excited to share our new study from the Jason Buenrostro Lab in nature! We developed a computational method for tracking transcription factor and nucleosome binding using single-cell ATAC-seq and deep learning. Paper: nature.com/articles/s4158…

What a beautiful home for our multiplexed organoids! Kudos to all the members of the Giuseppe Testa lab who contributed to the project. And a big shoutout to Philipp Dexheimer for this absolute piece of art!🎨

I am happy to share that our preprint about the modeling of #YY1 haploinsufficiency has been published as open access! You can find it here: nature.com/articles/s4138… #organoids #gabrieledevriessyndrome #ipscs #epigenetics Giuseppe Testa Alessandro Vitriolo Marlene F Pereira | PhD

New exciting discoveries about ADNP and its role in neurodevelopment!

3/ We ran simulations to estimate EP search times based on 1) measured subdiffusion, 2) physical/genomic distance. Within 300nm (~<200 kb), a gene can find 1000s of enhancers in minutes. Such encounters can’t be selective → EP selectivity needs other mechanisms, e.g. biochemical

This new preprint from my labmates provides a new perspective on chromatin dynamics! Strongly suggested to everyone into chromatin given its broad impact!