A mini-review on human endogenous retroviruses in Cell by me and Michelle Vincendeau. Enjoy! cell.com/cell/fulltext/…

Pircs et al. reveal specific deficits in autophagy in induced neurons from elderly Huntington’s disease patients, providing a rationale for autophagy activation therapies. bit.ly/3pZlwIx

Great opportunity. Great PI. Great Place!

Short commentary about autophagy and HD 🧠

Exciting new work on microRNA-alterations in Huntington's disease. Proud to have played a minor role in this study. A unique human dataset. actaneurocomms.biomedcentral.com/articles/10.11…

The proofed version of recent study using reprogrammed neurons to study HD and autophagy is now online. Enjoy!! academic.oup.com/brain/advance-…

A small text in Swedish about our HD research lu.se/artikel/ny-for…

Researchers reprogram human skin cells to aged neurons to study neurodegenerative disorders sciencedaily.com/releases/2022/…

This was a truly amazing collaboration between many labs, including Parmar Lab, The Barker / Williams-Gray Lab, kpircs, Johan Jakobsson and Daniella Rylander Ottosson. Thank you all for your contributions!

Get new insights about #autophagy in neurons derived from #Huntington's patients’ skin cells! Read the paper in Brain by Johan Jakobsson Parmar Lab Pia Johansson @raquelgarza95 Lund Stem Cell Center Medicinska fakulteten, Lunds universitet #CRISPR #neuroscience #neuralreprogramming doi.org/10.1093/brain/…

Swedish Medical Products Agency grants approval for clinical study of new stem cell based Parkinson’s Disease treatment: bit.ly/3yVd3Kz #parkinsons #parkinsonsdisease #medicine Cambridge University Parmar Lab michaeljfox.org

Wonderful Swedish christmas dinner with Parmar Lab Christopher Douse kpircs Anna Falk. Celebrating outstanding success in 2022!

New preprint from our lab. We asked if LINE-1 transposable elements are expressed in the human brain – and found something exciting and intriguing: L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification biorxiv.org/content/10.110… Thread👇

“Ten years ago I was kicked out and forced to retire.” Our new medicine laureate Katalin Karikó (Katalin Kariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges. Ten years ago, Karikó was still doing all her

New preprint from our lab! Great collaboration with the labs of Karolina Pircs and Csaba Kerepesi from Budapest. We built molecular aging clocks for the human brain using single-nuclei RNA-seq data. doi.org/10.1101/2025.0…

In our latest preprint, we introduce the first human cell-type-specific brain aging clocks from high-precision postmortem samples. Using single-cell transcriptomics, we uncover distinct aging patterns and new insights into neurodegeneration. #BrainAging biorxiv.org/content/10.110…

.Fresno State Ali Dadawalla '24 Semmelweis University attended EMBO Events Astrocytes workshop in Venice and presented his #Fulbright project research investigating astrocytic autophagy during aging via direct reprogramming of healthy patient-derived fibroblasts meetings.embo.org/event/25-astro…