
Institute of Molecular Immunology
@knollelab
#HBV #Tcells #tissueimmunity #antiviral #anticancer #immuneregulation #immunotherapy #preclinicalmodels #clinicaltranslation #imagingmassspec
ID: 1511593296409280515
06-04-2022 06:35:17
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Excited to share our latest publication in Science Immunology! We've uncovered an NK cell-mediated immune checkpoint (B7H6 : NKp30) that limits CAR T cell persistence, revealing new insights into immune regulation. #Immunology Broad Institute DKFZ science.org/doi/10.1126/scā¦




A single-cell in vivo CRISPR screen highlights genes driving T cell tissue adaptation and plasticity in autoimmunity Science Immunology science.org/doi/10.1126/scā¦





A second priming phase promotes high-affinity CD8 T cells by coordinating CD4 help and the relay of IL-2 in subfollicular LN niches. Congrats to WüSI - Systems Immunology Würzburgās Kasia, Deeksha, Kastenmüller Lab Georg Gasteiger . science.org/doi/10.1126/scā¦