Intriguing paper: Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone nature.com/articles/s4138…

Worth a closer read: Different projection neurons of basolateral amygdala participate in the retrieval of morphine withdrawal memory with diverse molecular pathways nature.com/articles/s4138…

Mouse behaviour hits the headlines! Dr Megan Jackson gives her opinion of what’s going on 🐭 UoBrisPhysPharmNeuro Bristol Neuroscience amp.theguardian.com/world/2024/jan…

We are excited to share our important findings showing that modulation of affective biases in rats is a neuropsychological mechanism shared by RAADs and could explain how their acute effects lead to sustained clinical benefits. Work of many years is out 🥳science.org/doi/10.1126/sc…

Rapid-acting antidepressant drugs modulate affective bias in rats | Nice work on psychedelics from Emma Robinson Psychopharmacology group & colleagues in Science Translational Medicine science.org/doi/10.1126/sc…

In a rat model, scientists examine how the rapid-acting #antidepressant molecules scopolamine, #psilocybin, and #ketamine rapidly reverse negative bias during behavioral tests and may modulate neural plasticity. Justyna Hinchcliffe UoBrisPhysPharmNeuro Psychopharmacology group scim.ag/5uP

New alternative to Rs only - #3Hs focus on lifetime experience of lab mice and rats and methods which increase their positive affective experiences and reduce cumulative suffering Psychopharmacology group Justyna Hinchcliffe Dr Megan Jackson Support The National Centre for the 3Rs Biotechnology and Biological Sciences Research Read more 3hs-initiative.co.uk

.3Hs Initiative: Housing, Handling and Habituation aims to improve the lives of laboratory rodents through housing, handling and habituation. With NC3Rs funding Prof Emma Robinson Psychopharmacology group quantify rodents' emotional experiences to build the evidence base for refinements. Webinar👉nc3rs.org.uk/events/3hs-ini…

" The 3Hs initiative focuses on housing, handling and habituation of laboratory rodents and methods which increase their positive affective experiences and reduce cumulative suffering." + webinar on march 27th thebehaviourforum.org/t/the-launch-o…

To hear more about our 3Hs Initiative in action join the webinar: nc3rs.org.uk/events/3hs-ini… 🐭🐀

Check our new website 🥳🥳 3hs-initiative.co.uk

Interested in motivation in mice? 🐭🐭 Come along to Caterina Marangoni’s poster on Friday: PS05-28AM-040 Effort-based decision-making versus spontaneous foraging tasks reveal divergence in antidepressant effects on motivation in mice University of Bristol School of PPN #FENS2024

My new paper is out 🥳🥳 If you are interested in our behavioural assays allowing us to measure emotional states in rats 🐀🐀 here are detailed protocols: dx.doi.org/10.1002/cpz1.1… University of Bristol School of PPN Bristol Neuroscience

Come along to Katie Kamenish’s poster PS05-28AM-044 on Friday to find out about the differences between 1st- and 2nd-generation antidepressants in Modulation of Affective Biases in Lister Hooded Rats 🐀🐀 University of Bristol School of PPN #FENS2024

Check out Katie Kamenish's (Katie Kamenish) poster today! #FENS2024 #UoBPPN

my poster is hanging up now!! can’t wait to meet everyone :))

Had a blast presenting my poster “Differences between 1st- & 2nd-generation antidepressants in modulation of affective biases in Lister Hooded rats” at #FENS2024 in Vienna this morning 🐀💉 thanks so much to everyone who stopped by!

TODAY at 13:00 in C42: PGR Snapshot Seminars from Rebecca Okubadejo, Cate Marangoni (Caterina Marangoni) and Katie Kamenish (Katie Kamenish)🧫🔬 More info: University of Bristol School of PPN Robin Corey Johan Alsiö UoBPPN Snapshot Seminars are generously sponsored by The Physiological Society #UoBPPN #PPNSnaps #PPNPGRs #PGR

NEW #OpenAccess PAPER OUT TODAY from UoB Palaeobiology! Here we explore the morpho-functional diversity of crocodile-line archosaur lower jaws, from their diverse origins in the Triassic to the crocodilians of today royalsocietypublishing.org/doi/10.1098/rs…

We asked three current life science PhD students for their top tips on making it through that all-important first week! 💪 Check out this great advice from Seph Nelson, Katie Kamenish & Shannon Lacey: ow.ly/EJts50Te5tU #PhDhelp #PhDsupport #PhDforum #PhDtips #PhDadvice