🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

So excited to be part of #ASHG24 !!! This will be my first time attending and I'll be presenting part of my PhD project 🤓 want to know about our work on transcriptomics & #SystemicLupusErythematosus ? Visit me Thursday (2.30pm) at the poster 5174👩🏽‍🔬🧑🏽‍💻 & lets talk about science

Really excited to have this out: a cell type-specific map of the impact of an understudied class of genetic variation (tandem repeats) on gene expression, at serious scale: nearly 1800 people with both WGS and blood scRNA-seq. So much signal!

Interested in how non protein coding variants influence protein expression? Visit our poster today to learn more! #ASHG2024 #ASHG24

New release of GWAS summary statistics for 2,502 clinical endpoints from FinnGen🇫🇮🧬 👉N>500,000 individuals, ∼10% of Finland's population 👉Together with UKBB, FinnGen offers the best resource for PheWAS out there 📊Instructions to access the data: finngen.fi/en/access_resu…

I took a huge pay cut NY -> Stockholm, but my living expenses also dropped by half - and it would have been more if we had kids. Many places in the UK have the unfortunate combo of ⬇️salaries and ⬆️ expenses, but many EU countries are totally competitive with the US academia.

Excited to present our new preprint: Topoisomerase IIb binding underlies frequently mutated elements in cancer genomes: biorxiv.org/content/10.110…. TOP2B ChIP to analyse non-coding drivers & mutational processes in 6k cancer genomes +in vivo validation of RMRP locus as a new driver.

Massive eQTL mapping of 3,734 lymphoblastoid cell line samples🧬 👉detection of master trans-regulators of expression 👉lupus risk allele in USP18 found to be trans-eQTL for 50 (!) genes 👉many trans-eQTL signals would be lost in bulk data w/ larger N 📰medrxiv.org/content/10.110…

Excited to launch the Helmholtz Munich | @HelmholtzMunich Imputation Server, enabling genotype imputation within the EU and beyond. Lots of plans for future development, reference panels and functionality enhancement rdcu.be/d0h3y

💡 New research highlight combines the data analyzed by Nightingale Health in Estonian Biobank and UK Biobank: unlocking genetic links to metabolite traits in a groundbreaking genome-wide association study! Researchers in a recently published pre-print have conducted a comprehensive

Massive analysis of metabolomic scores as predictors of 12 diseases in 700,000 participants❗️ 👉36 biomarkers from NMR metabolomics 👉score replication across UK Biobank/Estonian Biobank/Finnish THL Biobank 👉stronger effects on disease onset than PRSs 📜nature.com/articles/s4146…

Did you know that Germany has its own large-scale population-based biobank? The German National Cohort or NAKO NAKO Gesundheitsstudie If not, let me tell you why👇

Read this thread! Another example of how Europe is loosing competitiveness because of localism. thanks Marios Georgakis for sharing

Excessive data bureaucracy and gatekeeping slows the pace of science and reduces the value of expensive publicly funded resources. The UKB has been so successful in part because it avoided the trap of a few groups treating the data as their personal fiefdom protected by a moat of

Simon Harris- PM of Ireland is cooking here 🔥🔥🔥

Glad to share our preprint: "Origins and Implications of Intron Retention Quantitative Trait Loci in Human Tissues". This work, led by Eddie Park, started in 2019, but it took us a long time to understand certain aspects of our results and write the paper.🧵biorxiv.org/content/10.110…

Question to people working with UK Biobank data on UKB-RAP. DNAnexus, Inc. has just charged my credit card for 284.09 GBP but only sent an invoice for 37.40 GBP. Has this happened to anyone else? Super annoying, because I cannot get this reimbursed since the amounts do not match.

🚨 RECOMB-Genetics Deadline 🚨 The RECOMB-Genetics 2025 workshop is in Seoul 🌏 on April 25, 2025, just before the main RECOMB conference (April 26–29). 📅 Submission deadline: Feb 14, 2025 (AoE) 👉recomb.org/recomb2025/rec… Submit your work and join us for this exciting event!

Looking for weekend reading? I’m excited to share latest work from the group, a tour de force effort by the fantastic graduate student Yu Fu on the impact of chrX and dosage compensation on complex traits: biorxiv.org/content/10.110…