ERJ Open Research: The microbiome in bronchiectasis shows day to day variability in sputum samples from people with bronchiectasis and cystic fibrosis. This should be taken into account in studies of the airway microbiome in chronic airway disease. bit.ly/3URkv42

Online now: Optogenetic vagal nerve stimulation attenuates heart failure by limiting the generation f monocyte-derived inflammatory CCRL2+ macrophages dlvr.it/TLbc9J

The German Center for Lung Research (Deutsches Zentrum für Lungenforschung, DZL) kicks off its 2025 Annual General Meeting today, hosted by the DZL Heidelberg campus, the Translational Lung Research Center Heidelberg. #DZL2025 BMFTR DLR_de DLR - English Deutsche Zentren der Gesundheitsforschung (DZG)

Today I presented our work on neutrophil commensal associations in bronchiectasis sputum at the The DZL Academy in Heidelberg. Much of this work was performed by Letícya Melo and Shrutika Wadkar.

Our PhD student, Sina Dorn, presenting her preliminary results on sex relevance in COPD progression at the Systems Pulmonology research area of our institute Institute of Lung Health and Immunity

🚨 Postdoc position working with myself and Anand Shah on Bronchiectasis innate immunity. If interested and wish to discuss further please email or DM. jobs.nhs.uk/candidate/joba… Grateful for retweet.

Online now: CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo dlvr.it/TLy21K

Two weeks ago, I posted about this Cell paper. As it drew more attention than I'm used to, I wrote a longer piece with my thoughts. Beyond the points made before, I also address some of the feedback on the original tweet👇

European Respiratory Journal: Walking is more than a daily task, distance covered, or step count. Subtle, real-world gait patterns in individuals with COPD can offer valuable insights into overall health and support more personalised interventions. bit.ly/3H8M0Cn

Nice! Time to work on the mechanistic aspect of these associations in obstructive airway diseases!

Hot off the press in@ImmunityCP! 🔥 Proud to share our new perspective — a collaborative effort with fantastic colleagues — proposing a unified framework to classify neutrophil subpopulations. #ThePowerOfMany 👉tinyurl.com/ye22e9fx

Endotypes of Pseudomonas aeruginosa Infection in Bronchiectasis Are Associated with Inhaled Antibiotic Response: Results from Two Randomized, Double-Blind, Placebo-controlled Phase III Trials (ORBIT 3 and ORBIT 4) James D Chalmers Rebecca Hull 🔗 tinyurl.com/ubcw6f8w

The Blue Journal thanks Rebecca Hull, PhD, for her contribution to the August issue Endotypes of Pseudomonas aeruginosa Infection in Bronchiectasis Are Associated with Inhaled Antibiotic Response Rebecca Hull James D Chalmers University of Dundee atsjournals.org/doi/full/10.11…

Gene-Set Enrichment Analysis and visualization on the web using EnrichmentMap: RNASeq. #GSEA #WebTool #RNAseq Bioinformatics Advances academic.oup.com/bioinformatics…

Journals can’t find peer reviewers. Preprints aren’t taken seriously. Garbage papers slip through peer review. Meantime, AI is slowly taking over. Nature describes the current situation. I highly recommend reading the article. 📍 The summary (+ my comments): 1. We are facing a

A cost-effective ultra-high-throughput cytometry-based framework for the detection of physical interactions between cells, along with the characterization of complex cellular landscapes Nature Methods nature.com/articles/s4159… nature.com/articles/s4159…

This was so much fun to write, thank you Fil Swirski & Scientists and @realFlorentGinhoux !! A summary of the many surprising jobs that immune cells do after hours (and it is more than just cleaning up) Immune system influence on physiology | Science science.org/doi/10.1126/sc…

Online Now: CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases dlvr.it/TMMfzY

Come and join us for this exciting research seminar in Barcelona ERS EMBARC

Here's our take on how neutrophils can be a critical link between cancer and cardiovascular disease! "Heart of the matter: Neutrophils, cancer, and cardiovascular disease", just published Journal of Experimental Medicine with Saira Ambreen, Afshan McCarthy and Andrés Hidalgo rupress.org/jem/article/22…