KaelinLab
@kaelin_lab
William Kaelin’s lab of @DanaFarber and @HHMINEWS and @harvardmed. We love hypoxia, tumor suppressor proteins, up-assays, and most of all controls.
ID: 1095852027920506880
https://kaelinlab.dana-farber.org/ 14-02-2019 01:07:38
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We report that Cyclin D1 is an important direct target of HIF2 that drives the proliferation of ccRCC. Our findings further support the notion of combining HIF2 and CDK4/6 inhibitors to enhance antitumor activities. Congrats to Nitin Shirole and the team!