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Lipid membranes serve an unexpected role in NK cell functionality protecting them from autolysis, while degranulation allows for the inherent lytic granule membrane properties to create local ordered lipid "shields" against self-destruction.@jordanorange

Our new story on virtual memory T cells is out Science Immunology. (1/5) Virtual memory T cells orchestrate extralymphoid responses conducive to resident memory immunology.sciencemag.org/content/6/62/e…

Relevance of Polymorphic KIR and HLA Class I Genes in NK-Cell-Based Immunotherapies for Adult Leukemic Patients dlvr.it/S5GcCd

How the immune system shapes atherosclerosis: roles of innate and adaptive immunity dlvr.it/S5bWLT

5 new consult patients since last PM K: 6.1 (anuric), 7.0, 6.4, 7.6, 7.4.

Optimal anticoagulation for A Fib for people on dialysis is a clinical dilemma. Nahel Elias and I suggest that transplant candidacy be part of the discussion. Thanks JASN_News American Society of Transplantation (AST) ASTS #Transplant

AUTOIMMUNE DISEASE, BY THE NUMBERS from ⁦Scientific American⁩

(1/3) Why is BCL6 absolutely required in T cells to support germinal center formation? Is it all because BCL6 specifies T cell fate in a strictly cell-intrinsic manner? Please check our latest work online Immunity. Link and bullet points below.

#kidneyomics

Excited to share our latest publication in the Journal of Clinical Investigation Journal of Clinical Investigation! JCI - The self-peptide repertoire plays a critical role in transplant tolerance induction jci.org/articles/view/…

Inclusion criteria: how NK cells gain access to T cells: buff.ly/3z633eI #Commentary by Tonya J. Webb UMGCCC Related article: buff.ly/3nro0P1

Just in time for American Society of Nephrology #KidneyWk, check out this incredible imaging of the kidney from the Nature Methods paper below. Swoon 😍 nature.com/articles/s4159…

Thank you Ella Marushchenko for an incredible cover art in @advfuncmat. Together with Jamil R. Azzi MD, PhD lab we developed a theranostic microneedle platform for the simultaneous delivery of immune modulators and sampling of skin interstitial fluid to monitor response to the therapy.

Despite systemic reconstitution of CD4+ T cells, HIV+ patients who started antiretroviral therapy late after diagnosis show an irreversible depletion of tissue-resident memory T cells in the skin and mucosa cell.com/immunity/fullt…

⚕️What if we could avoid the need for human leukocyte antigens matching for successful organ transplants without severely impairing the recipient’s immune system? 🧬Leonardo Ferreira has a story to tell you! 📰Read more: bit.ly/3E8RCGc #AcademicTwitter #scicomm #SAi #data

Fully agree with the editorial by Ilkka Helanterä Michael Mengel in American Journal of Transplantation on the need for more consensus on the effective treatment (and prevention by matching?) of TCMR - still very deleterious despite the use of strong immunosuppressants! @VDRFHSUM onlinelibrary.wiley.com/doi/full/10.11…

Here it is again Science Magazine thanks to all involved in this! Test Account

For all the times you’ve brought a smile😄 and made all our days seem brighter ☀️ Happy #InternationalWomensDay 🌸 to strong, intelligent, talented women! Zhabiz Areej @ChristaDeban Nour K Younis #Rania #kate 👩‍🔬

Proud dad moment 🤣 #chloe

Found this antique while cleaning my office. Is this the “pink sheet”?