The Victors™️ #GoBlue

HAIL! #GoBlue | Meijer

For the 44th time in program history, the Michigan Wolverines are Big Ten champions! #GoBlue

𝗘𝘅𝗽𝗲𝗰𝘁𝗮𝘁𝗶𝗼𝗻–𝗠𝗮𝘅𝗶𝗺𝗶𝘇𝗮𝘁𝗶𝗼𝗻 (𝗘𝗠) 𝗮𝗹𝗴𝗼𝗿𝗶𝘁𝗵𝗺 is an iterative method to find (local) maximum likelihood estimates of parameters in statistical models, where the model depends on unobserved latent variables. #Python code for Gaussian Mixture Model.

Our free Single Cell Genomics Day workshop starts tomorrow at 10AM EST! You can ask watch the Youtube livestream at satijalab.org/scgd. See you soon!

A 🧵 on some of my intuitions/priors about the genetics of complex and molecular traits in humans (i.e. what I think of as typical), largely motivated by GWAS/QTL studies over the past decade [citing papers with nice figures where possible]

A 🧵 on algorithms for predicting regulatory variant effects to help understand complex disease. IMO an extremely challenging problem that's at a glass mostly full / glass mostly empty point right now depending on who you ask.

网友投稿 “看苍生” 6月1日，一部名为《人民》的视频在B站爆火 视频中平凡人生活中的艰辛与快乐引发大量网友共鸣。

The first step of learning computational biology is to learn unix commands. Get this FREE 6-page PDF with over 150 useful Unix commands! #unix #computationalbiology #bioinformatics buff.ly/3NO3uVt

I'm delighted to release the first half of my new open-access online textbook in human population genetics: web.stanford.edu/group/pritchar…

My colleague Francesca Luca will be presenting at 11:25 a.m.   "Translating Genetics to Function: One (effect) size does not fit all (contexts)" in the first session. Many interesting talks to discuss recent advances and current challenges. Looking forward to connect via zoom.

Functional characterization of eQTLs and asthma risk loci with scATAC-seq across immune cell types and contexts dlvr.it/T0bNYr

Rose Bowl champions are maize and blue! #GoBlue

"Business is finished." 🎥 National Championship Game Mini Movie #GoBlue

📢'The World Is Your Oyster' is for those who are born in global north countries--don't experience visa bureaucracy & emotional burden that non-white global south scholars do. Citizenship is a privilege that we need to recognize in the academe. 1/n nature.com/articles/d4158…

Really excited to share our new review paper on GxE! Team work with three graduate students: Carly Boye, Shreya Nirmalan, Ali Ranjbaran link.springer.com/10.1038/s41588…

Looking forward to participating and presenting our work w/ Roger Pique-Regi on "Gene expression changes in immune cells during the peripubertal period" nia.nih.gov/research/works…

Ready, set, go! First experiment in the new lab is underway. Thanks to Shreya Nirmalan and Gabrielle Garlicki the Luca Lab is up and running at UChicago!

We have released Version 3.1 of FastENLOC for colocalization analysis (github.com/xqwen/fastenlo…). The new version includes many new features and a revamped user guide (xqwen.github.io/fastenloc/). For one, you can now estimate colocalization priors with only summary-level data.

🚀 Unveiling asthma's genetic puzzle! 7 immune cell types analyzed via scATAC-seq reveal how 25+ eQTLs in CREs influence 300+ genes. #AsthmaResearch PMID:39814021, Am J Hum Genet 2025, AJHG cell.com/ajhg/fulltext/… #AI #Pharma #BioMed #RNA #ASHG #ESHG