CDC Director Dr. Rochelle Walensky: “Our data from the CDC today suggest that vaccinated people do not carry the virus.”

Finally now out in Science Immunology ! Great collaboration and a long road with Iivo Hetemäki @nellimarikki Joona Sarkkinen @varjosal Translational Immunology Research Program (TRIMM) Reetta Vanhanen and so many others key people not on Twitter! A quick 🧵on our findings science.org/doi/10.1126/sc…

Fantasiassani olen päässyt päättämään Suomen koronalinjauksista. Pidän täällä Twitterissä nyt tiedotustilaisuuden uusista linjauksista, pitäkää hatuistanne kiinni! Koska en poliitikko en oikeasti tiedä miten nämä lainopillisesti menevät mutta sitä vartenhan on virkamiehet 💪🏻

Vaikea ymmärtää Etelä-Suomen AVI:n päätöstä liikunta- ja harrastustilojen rajoitusten jatkamisesta. Sairaalakuormitus on ollut stabiili yli viikon. Nämä rajoitukset aiheuttavat merkittävää haittaa ihmisten hyvinvoinnille eikä niitä voi jatkaa vaan varmuuden vuoksi.

JUST IN: #Russian state TV channels have been hacked by #Anonymous to broadcast the truth about what happens in #Ukraine. #OpRussia #OpKremlin #FckPutin #StandWithUkriane

New results from our group 🌟, project lead by Joona Sarkkinen and now published in Modern Pathology. We studied thymus histology Finnish Biobanks – FINBB in rare autoimmune disease myasthenia gravis with generous support from @EJPRareDiseases TARID consortium rdcu.be/cJPmg. Small🧵

Myasthenia gravis is a autoimmune disease where autoantibodies targeted againts nerve-muscle junction cause severe muscle weakness. Thymic pathology is often present and esp in early-onset MG, thymectomy alleviates symptoms. We confirmed earlier findings that extopic germinal

centers are common on EOMG thymi but could also show that the eGC number directly correlates with the patient’s outcome after thymectomy. eGCs were rare in patients over 45 yrs. Pathology of the thymus is thus clearly different in early and late onset diseases.

For me as thymus-enthusiast the most interesting finding was that women woth MG (mostly EOMG) had larger area of Hassall’s corpuscles, those small clusters of epithelial cells in the thymus that nobody really knows what their function is 🧐.

This is our first report from the TARID consortium - stay tuned, we have much more exciting research into MG and extopic germinal centers in progress. One might wonder why to study a rare autoimmune disease when there are more common ones. In MG we know that the autoantibodies

that are central to pathology, are produced in the thymus. MG is an unique opportunity to study autoantibody production in situ! This information could help understand autoantibody production in other diseases as well.

This work would not have been possible without QuPath and Finnish Biobanks – FINBB sample collections. Funding from @EJPRareDiseases made everything possible. Thank you all co-authors and of course Joona Sarkkinen who did all the work! Full article here: rdcu.be/cJPmg

Old friends reunited in CML! 🤝 Our study of a clinical trial shows that the addition of IFN-α curtails the immunological effects of dasatinib in CML, out now in Journal of Clinical Investigation. More about the study and immunology in CML in a slideset below: 🧵 tinyurl.com/yckz58uk

Nöyrin kiitos Instrufoundation väitöstyöprojektilleni myöntämästänne tuesta!

What are tertiary lymphoid structures (TLSs)? We found evidence of adaptive immunity in #ovariancancer. Check out our #bioRxiv preprint biorxiv.org/content/10.110… Great collaboration with Joona Sarkkinen Eliisa Kekäläinen

Several Fifa officials arrested over US corruption charges in dawn raid at Zurich hotel, source confirms to BBC bbc.in/1F9Noaw

Sepp Blatter has resigned as FIFA President after 17-years in charge. Victory for all of football. (Source: Everyone)

Suomi 2015: kansanedustaja leikkii Hitleriä, ei seuraamuksia. Tekstiviesti blondille, pakko erota. #Immonen

José Mourinho's payout is expected to be a huge £40m. Forty-million-pounds. (Source: Daily Mail)