A truly excellent summary of our latest research by the great Dr. Slotkin:

Cool seeing our research gaining interest from folks like Bryan Johnson who are pushing the boundaries of health optimization ! Monash University

Why heart attacks peak in frequency and severity in the early morning hours: a pair of circadian clock-related proteins appears to be the underpinning nature Nature News & Views nature.com/articles/d4158… nature.com/articles/s4158…

Incredible piece of journalism:

Joe Mazzulla to John Karalis 🇬🇷: “You don’t pick the tests you have. You pick how you respond to them.”

Wow. Just sat through the announcement of the comprehensive report from the Make America Healthy Again Commission The White House. This is the first time the federal government has actually said and documented we have a problem with chronic disease in this country and they want to do

In Science Magazine today, my essay on predicting and preventing Alzheimer's disease (open-access) science.org/doi/10.1126/sc…

Powerful point. In many cases, we still don’t know whether circadian disruption precedes mental disorders or is a consequence of them. There’s still a lot of research needed to tease apart these relationships.

exercise improves disease-free and overall survival after cancer independent of weight loss. first level 1 evidence !

Further consequences of late night gym sessions on sleep and circadian rhythms ⬇️

Congratulations to the inimitable Dr Mark É Czeisler, MD, PhD ! 🕰️🫀

Big news: Massachusetts General Hospital ranks #1 in the world for high-impact research contributions among healthcare institutions, according to the 2024 Nature Index! 🌍 Mass General Transplant Mass General Surgery MGH Pathology Mass General Brigham Nephrology Mass General Brigham Research nature.com/nature-index/n…

Going to bed earlier links with increased moderate-to-vigorous physical activity the next day Shown in 2 independent cohorts, ~26,000 participants w/ WHOOP, fitbit sensors AllofUsResearch PNASNews Josh Leota Monash University pnas.org/cgi/doi/10.107…

Out today in PNAS, we explore how sleep habits – and nightly changes in sleep – may link to next-day physical activity. In two large-scale wearable sensor studies (~6.5 million nights from ~26,000 individuals), we found: 1. Longer sleep duration and later sleep timing were

💤sleep timing/duration→🏃‍♀️next-day physical activity 1️⃣early🐦 exercised more than night🦉 2️⃣ earlier sleep timing w preserved duration was the strongest daily predictor of exercise kudos Josh Leota for the sophisticated analysis & WHOOP AllofUsResearch for real-world data

Sleep duration and timing are associated with next-day physical activity: Insights from two large-scale wearable sensor studies | Josh Leota, Mark É. Czeisler, Flora Le and Elise R. Facer-Childs, PNAS Significance Physical activity (PA) has been widely recommended to improve

Go to bed early if you want to crush your exercise goals. A study of ~20,000 users of a fitness watch found that people who fell asleep at 9:00 p.m. exercised 44% longer the next day, compared to people who went to bed at 1:00 a.m. In PNAS: ow.ly/qgnx50WlN93

Thank you, Will Ahmed! See our research with WHOOP below:

Avoid high intensity exercise 4 hours before sleep

How we sleep is intricately linked with how we move! Thank you, Alvin Powell and the Gazette, for covering our latest led by @JoshLeota with WHOOP AllofUsResearch in the Dr Elise Facer-Childs group Monash University news.harvard.edu/gazette/story/… Brigham and Women's Medicine Residents Harvard Medical School