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I want to go on record and say that I have never had any doubt in the defense no matter what else I have tweeted

BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

Won't back down

Our first foray into the synthesis of opioid antagonists. #opioids Total Synthesis J Org Chem/Org Lett Dearomative Access to (−)-Thebaine and Derivatives | Organic Letters pubs.acs.org/doi/10.1021/ac…

🚨 Kindly RT🚨 Calling all motivated Postdoctoral fellows with expertise in synthetic organic chemistry, Pd Chemistry, and methodology development! 🧪 Explore exciting projects with us at Hebrew University. Position starts March-April 2024.[1/2] Chemjobber RealTimeChem (no longer active) #postdocjobs

devastated. heartbroken. In so much disbelief rn, I wish my leg broke earlier in the season so y’all could see this team is much more than the quarterback. I thought results matter. 13-0 and this roster matches up across any team in those top 4 rankings. I am so sorry. Go Noles!

#chemtwitter is there a cheaper alternative to sclareolide? I remember reading a paper mentioning an alternative building block that is very similar but I can’t find it.

Sometimes, labeling things can be good. Check out Zach's latest work in J. Am. Chem. Soc. below: pubs.acs.org/doi/10.1021/ja…

Does anyone have any workup/isolation tricks for dealing with the byproducts of a reaction using Martin’e sulfurane?

Excited to finally share the next story of my PhD! We explored the photocatalytic coupling of phenols and pyridines to make a new class of pyridinium salts! Kozlowski Lab Penn Chemistry J Org Chem/Org Lett pubs.acs.org/doi/10.1021/ac…

Optical Control of G-Actin with a Photoswitchable Latrunculin J. Am. Chem. Soc. #Chemistry #Chemed #Science #TechnologyNews #news #technology #AcademicTwitter #AcademicChatter pubs.acs.org/doi/10.1021/ja…

Today in ChemRxiv, we utilize catalytic pyridinium additives alongside an Ir photocatalyst to facilitate photochemical amination of phenols and halophenols. Many thanks to Cindy and @ynliu217 for all their help!🎉 Kozlowski Lab Penn Chemistry chemrxiv.org/engage/chemrxi…

🚨NEW PREPRINT🚨 We serendipitously discovered a unique quinoline amination reaction! Using Py-HVI we get mixtures of C2 and C4 aminoquinolines. (1/4) chemrxiv.org/engage/chemrxi…

Imagine a carbocation that eliminates… not to form a C=C double bond as we teach in orgo, but rather a C-C single bond to a remote position. Sounds like science fiction? It’s in Science Magazine alright! Read here science.org/doi/10.1126/sc… Austrian Academy of Sciences CeMM University of Vienna STEM Universität Wien

全合成研究の皆さん、凄いのありますよ！ 初の単離報告らしいので、合成レースが始まりそうな予感。 構造の複雑さにもかかわらず、NMRはシンプル pubs.acs.org/doi/10.1021/ac…

🕰️ In this Synfact Classic Dirk Trauner and Christoph Etling highlighted the ‘Total Synthesis and SAR Studies of the Neurotrophic Sesquiterpenoid Jiadifenin` reported by Danishefsky SJ and colleagues from Memorial Sloan Kettering Cancer Center and Columbia University in 2006. 🧪 👉 brnw.ch/21wLJEz

#TotalSynthesis of the Norcembranoid Scabrolide B and Its Transformation into Sinuscalide C, Ineleganolide, and Horiolide by Davy S. Lin, Georg Späth, Zhanchao Meng, Lianne H. E. Wieske, Christophe Farès, and Alois Fürstner Max Planck Society in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…

Azorellolide! How can you not work on a natural product that starts with "Azo"? Great collaboration with Tantillo Lab. I have to say my respect for carbocations has enormously gown through this project. They are just too high in energy and have too many options. But you can tame