This isn't science fiction. This is real sequencing biotechnology just introduced by Roche. Wild and wonderful.

🚨 mRNA cancer vaccines aren’t just "tumor antigens + new delivery." Key diff: ✅ Target neoantigens (personalized, not shared) ✅ Pair with immunotherapies (checkpoint inhibitors) ✅ Rapidly adaptable to mutations Success hinges on combo approaches. Too early to call "flop." 🧬

DERM AI now legally authorized to make clinical judgment without dermatologist oversight. 99.8% accuracy, dermatologists: 98.9%. NHS hospitals use DERM to identify benign lesions without dermatologist review, enabling same-day patient discharge. Ethan Mollick Bryan Carmody

Med19: Anti-aging hero or cancer villain? 🧬 Today's research shows Med19 upregulation: ✅ Literally almost doubles lifespan! ⚠️ BUT is overexpressed in human cancers (lung, liver, etc) Will it help or induce cancers in humans? Thankfully: Flies showed no tumors with Med19 boost!

For medical students and new doctors, a career in Medicine looks more and more like a serious mistake with every AI advancement. Bryan Carmody x.com/SRSchmidgall/s…

Stanford, UCSF, UCLA, etc - why could the world's top hospitals not diagnose a simple case of scabies? It's bc new patients are likely to be seen by Mexican/Hispanic docs who're known for unimaginable blunders. But physicians don't want to be called a racist, so we say nothing.

France's holocaust.

Baffling: PGNMID, monoclonal no more I got this consult case as immune complex-MPGN LM- MPGN pattern IF- IgG, C3, C1q, kappa & lambda 3+ Did IgG subtypes-IgG3 3+, all others negative EM- mottled deposits Dx- Proliferative GN, IgG3, but ? with monoclonal IgG deposits (PGNMID)

Some time yesterday, my hospital forced me to turn into Malcolm X's house negro. Deleting controversial posts that I can find, per the hospital's directive.

OpenEvidence has revenue of $50 million - but a valuation of $6.1 BILLION. Question for all the “AI can’t replace doctors!” naysayers: What do *you* think OE’s long-term monetization pathway looks like? What are investors expecting will happen to justify this valuation? 🧵

This is legit 2022 research by the Babraham Institute.

Standards for academic tenure have already eroded to the point of being meaningless. I’ve seen tenure granted not for scholarship or teaching, but for being friendly with the administration. External review is often a rubber stamp, internal review is a political game, and the

Releasing a new "Agentic Reviewer" for research papers. I started coding this as a weekend project, and Yixing Jiang made it much better. I was inspired by a student who had a paper rejected 6 times over 3 years. Their feedback loop -- waiting ~6 months for feedback each time -- was

Rich students had "AI help" for generations - they hired tutors who did all your homework. Now that poor students can also get the same form of help, people suddenly want to end homeworks and take-home exams?