🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

If you missed Dr. John Hickey's talk today on "From Molecules to Multicell Modules: Immune-Mediated Tissue Restructuring" as part of the Sunbelt Spatial Omics Seminar 1 (sites.gatech.edu/sunbeltspatial…) here is the YouTube link: youtube.com/watch?v=_Hle_8…

Rising-star seminar series. We are hosting e-seminar of John Hickey John Hickey Immune-mediated Tissue Restructuring: A spatial-omics perspective March 28, 9am Singapore/Beijing/Hong Kong time Zoom: hku.zoom.us/j/7970766995

The Spatial Human #Macrophage Map is finally online in Cancer Discovery! We show how phenotypically distinct macrophage populations occupy spatially segregated tissue #niches, with #IL4I1 and #SPP1 TAMs predicting opposite outcomes in colon cancer!

Ever wonder more about different flavors of human macrophages and if they are restricted to certain spatial locations in tissues? This paper has the data and insights you are looking for! 🔥

One hope of biology is to collect enough data to model "reality" in the computer. This could allow one to ask/answer questions that are nearly impossible to ask in the lab. Here, we show that collecting the raw data on cell positions in multiple stages of a mouse cancer model

.John Hickey et al. integrate multiplexed CODEX tissue imaging with multiscale modeling, showing that initial T cell phenotype affects tumor conversion to anti-proliferative state, critical for controlling growth rate. Structural reprogramming also maintains T cell phenotype,

Explore the power of #PhenoCycler #multiplexed imaging with today's #FridayRead, centered on two groundbreaking studies published in Cell Press Journals. The first study provides in situ mechanistic insights into temporal tumor microenvironment changes, cell interactions

Alex Xu Science Advances Akil Merchant Beth Karlan Congrats Alex!

Sunbelt Spatial Omics Seminars! Dr. Yuqi Tan (Yuqi Tan Ph.D.) Stanford University May 3, 2 pm EST Title: SPACEc: A Streamlined, Interactive Python Workflow for Multiplexed Image Processing and Analysis Register: lnkd.in/eSH5tEy2 (Advised by Rong Fan )

Thanks, Ahmet for the invite! I am looking forward to sharing SPACEc with the spatial community on May 3rd.

What drives the success of adoptive T Cell therapy? Should researchers engineer these therapies in a way that prioritizes cellular microenvironment manipulation to yield more productive anti-tumor immune responses? New papers by John Hickey suggest so. bit.ly/3KboSkL

How can spatial technologies be used to analyze tissue morphology before & after #cancer treatment? #Melanoma researcher John Hickey will share his insights in this free webinar. 🗓 Tuesday, May 28 ⏲ 9 am PDT/12 pm EDT/5 pm BST/6 pm CEST selectscience.net/register.aspx?…

Thanks to Maria Brbic and Sebastian Waszak for the invitation to give talks at EPFL! It was also awesome to share our update on SPACEc in the Single-cell Genomics GRS. Special shout out to Rong Fan and XIAOWEI ZHUANG for organizing such an amazing conference! See you in 2 years!

Once again, it’s time to test your intestinal fortitude with a gut-busting #CODEX image of the inner workings of your #intestines from #_hubmap researcher John Hickey. After some masticating & ruminating, you’re sure to get through to the bottom! @stanford @garrypnolan @dukeU

Join us for an enlightening webinar featuring Dr. John Hickey (John Hickey) from Duke University as he showcases the approaches his team has developed to dissect intricate tissue datasets and bridge connections across molecular and multicellular scales. bit.ly/3zGs8CR

Thanks to our team Kalen Clifton Mayling Chen Lyla Atta Brendan F. Miller as well as our collaborators Skylar Li Rahul Satija John Hickey for contributing to the project, to Dr. Jean Fan for guidance and mentorship, and to reviewers for providing helpful, thoughtful feedback! 10/10