Joe Chakkalakal
@joechakkal
Associate Professor Duke University; Orthopaedic, Cellular, Developmental and Genome Laboratories; Neuromuscular, Stem Cell, Regeneration, and Aging Biology
ID: 3872245672
https://sites.duke.edu/chakkalakallab/ 05-10-2015 15:26:02
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Agingdoc⭐David Barzilai🔔MD PhD MS MBA DipABLM🩺 Matt Yousefzadeh Just to note that the authors analyzed juvenile and middle aged mice. 6 weeks versus 42 weeks old! This is likely a maturation phenotype not an aging phenotype.
We have moved to Duke U, where we’ll continue to study neuromuscular development, regeneration, and aging. Looking to fill various positions including graduate and postdoctoral. Please contact me/please share. Duke Orthopaedics Duke Cell and Molecular Biology Graduate Program Duke DSCB Duke Regeneration Center Duke Graduate School
Why do we have two H3K27 demethylases - UTX and JMJD3? Muscle stem cells require both proteins to respond to muscle injury. Kiran Nakka showed that JMJD3 turns on genes that modulate the inflammatory response while UTX turns on genes to make new myofibers. science.org/doi/10.1126/sc…
Congrats to Tom Cheung & colleagues for their new iScience journal paper: Global Chromatin Accessibility Profiling Analysis Reveals a Chronic Activation State in Aged Muscle Stem Cells. tinyurl.com/35533nna
Using different cell systems Tom Cheung and our lab have identified the same enhancer directing Pax7 expression. cell.com/cell-reports/f… cell.com/iscience/fullt…
Congratulations to incoming PI Pura Muñoz-Cánoves and her team on their paper in Cell Stem Cell illustrating that mitochondrial dynamics are required for tissue regeneration. cell.com/cell-stem-cell…
We are looking to hire for a faculty position in the biology of rehabilitation, exercise, and/or movement in MSK disease, development, or regeneration Duke Orthopaedics. Apply at academicjobsonline.org/ajo/jobs/22597
Your every breath depends on the diaphragm. Ever wonder how that muscle develops? See our new paper! Wonderful work of Liz Sefton Dr. Brittany Collins and Mirialys, Claire, Mary, and Allyson not on twitter. doi.org/10.7554/eLife.… eLife - the journal
Very excited to share our latest work in JCI insight! We performed spatial transcriptomics on volumetric muscle loss & found a cool fibrotic cell patterning! This was led by U-M BME student Jacqueline Larouche! 1/n insight.jci.org/articles/view/…