Great discussion on Type 1 error in #noninferiority trials via Venk Murthy MD PhD Important consideration for #cancer NI trials #radonc #pcsm I’ve heard Howard Sandler mention these issues before Drew Moghanaki Jeff Michalski Daniel E Spratt Dr. Andrew Loblaw Alison Tree 💙 x.com/venkmurthy/sta…

Is “The Gross Clinic” by Thomas Eakins the most Important American painting?” buff.ly/37FrumO

academic.oup.com/biostatistics/…

Neil Peart's love of literature and reverence for history deeply informed his songwriting. Read Annie Zaleski's remembrance of the Rush drummer and lyricist: trib.al/vv7iGRv

“There are three things we should do everyday: we should laugh; we should think; and we should have our emotions moved to tears.” —Jimmy Valvano facing #cancer and teaching us how to live

ORIOLE out in JAMA Oncology: bit.ly/33OAKmR. Metastases directed #SBRT improves PFS over observation. Great work by Phuoc Tran & team. IMHO confirmation needed on larger trial, active comparator (ADT at least) & more robust endpoint. But a great step in right direction.

Fauci is my hero. “‘I do believe that one gets unique insights into disease when you actually physically interact with patients,’ he says. In the case of Ebola, Fauci says he also wanted to show his staff that he wouldn't ask them to do anything he wouldn't do himself”🙏💪

Bill Gates interviewed for The Economist on covid. Well worth watching. You get a sense of a person who spends his time learning, absorbing tremendous knowledge, seeing the big picture, and trying to do something to make it better. youtube.com/watch?v=m7Stkv…

Is there no one in power in Dem Party w/ spine to say “you know, we can fix a few things about drugs, like making sure they all go generic w/o delay, but let’s not pretend like drug spending is THE problem. OOP costs are. Let’s reform insurance & preserve innovation.”?

Contemporary philosophy

Payors have embraced the Age of Misdirection—meaning cleverly deflecting the blame for high healthcare costs, while enjoying record profits. Shocking? Not really. Read what health plan executive turned whistleblower, Wendell Potter, has to say about it. bit.ly/2U9P4WL

The overhead view makes Rich Strike's comeback for the upset Kentucky Derby win look even more incredible. 😮 #KyDerby | Churchill Downs

Congress is on the verge of gutting cancer & Alzheimer’s R&D w/ a few careless lines in reconciliation bill b/c seemingly everyone is tired of trying to do the right thing & thinks no one will notice. You’ll never want to contribute to a campaign after this reading this. 1/20

One might think that this is all Congress needs to see to recognize what it needs to do (hint, current senate bill is awfully generous to PBMs and patients still don’t get first dollar coverage… can you fix that?). And yet… No Patient Left Behind

Photo finish at the Derby. Mystic Dan. Wow Kentucky Derby #KentuckyDerby

“I was neither angry nor scared. It simply was. It was a fact about the world, like the distance from the sun to the Earth.” Revisit an excerpt from Paul Kalanithi’s posthumously published memoir, “When Breath Becomes Air.” nyer.cm/Q4zcILB

Today is HCC day! - RTOG 1112 - HCC unsuitable for or refractory to local-regional Tx (n=177) - SBRT & Sorafenib vs Sorafenib - After adjustment for stratification factors, improved OS after SBRT (HR 0.72) - Median PFS improved from 5.5 to 9.2 mo (HR 0.55) jamanetwork.com/journals/jamao…

SOVEREIGNTY TURNED ON THE JETS DOWN THE STRETCH TO WIN THE 151ST KENTUCKY DERBY! 🌹👏 #KyDerby

This shot from NFL Films is unbelievable