📣Sharing the latest research from the Miguel Ramalho-Santos Lab, just released on bioRxiv! We found LINE1 RNA promotes nuclear compartmentalization to repress the 8-cell state in human embryonic stem cells. biorxiv.org/content/10.110… 👇Key findings:

Glad to share the peer-reviewed version of the Matthew G. Heffel manuscript now in nature. In collaboration with Paredes Lab , we studied the chromatin conformation and DNA methylation changes during human hippocampus and frontal cortex development. nature.com/articles/s4158…

Excited to share my lastPhD publication! We discovered non-inherited mutational patterns in schizophrenia occurring before birth. Huge collaborative effort w/ Vladimir Seplyarskiy Attila Jones science.org/doi/10.1126/sc…

Topic collection on Brain Cancer – Exploring Genetic and Epigenetic Mechanisms - in Neurogenetics - submissions are welcome, check here for further details: link.springer.com/collections/ge…

Delighted to see the completed Special Issue of Current Opinion in Genetics and Development on "Genome Architecture and Expression” It was a pleasure putting this together with Maya Capelson. Thanks to all the authors that contributed articles sciencedirect.com/special-issue/…

1/ 🧵 So excited to finally share our preprint! Long-read sequencing of hundreds of diverse brains provides insight into the impact of structural variation (SV) on gene expression and DNA methylation- A new genomic resource for brain research! 🧠✨biorxiv.org/content/10.110…

Check out our narrative review published in the new npj_Women's Heath "The biomechanics of the vagina: a complete review of incomplete data" written with the ultimate expert on vaginal biomechanics Raffaella De Vita UC San Diego OBGYN npj Journals "...By strengthening collaborations among

A great resource: tandem repeat database in ⁦AllofUsResearch⁩ with the expert input of ⁦PacBio⁩ ⁦Mike Eberle⁩ ⁦Egor Dolzhenko⁩ search.app/zkzCsN5Yx7Frwj…

📢 CUT&Tag version 3 Sometimes the preprint to paper route can be quite the odyssey. And so in that vein, we are delighted to give you version 3 of our CUT&Tag optimization and benchmarking manuscript: biorxiv.org/content/10.110…

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis

How did humans develop unique traits despite sharing nearly identical genomes with other primates like chimpanzees? Together with Han Yang (Han Yang), our new study on human accelerated regions (HARs) sheds light on this question @ nature.com/articles/s4158…. 1/12

Join us next Tuesday from 12:00-1:00 at UMB for another Baltimore Brain Series seminar! Awardees Dr. Bradley Keegan from NIDA and Bailey Spiegelberg from UMB will present their exciting work. Zoom link provided upon request! Univ of Maryland School of Medicine Neuroscience

LINE-1 ribonucleoprotein condensates bind DNA to enable nuclear entry during mitosis | Science Advances science.org/doi/10.1126/sc…

#PeeWeeAsHimself is this year's highest-rated TV show. editorial.rottentomatoes.com/guide/best-new…

Are you passionate about harnessing innovative brain organoid technologies to explore the mysteries of neurodegenerative disorders? Would you like to pursue a Postdoc, MSc or PhD degree in Medical Neuroscience? Join our exciting journey of discovery!

1/ Just out in Nature Medicine : we show the opioid system modulates ketamine’s effects in major depressive disorder, with naltrexone pre‑treatment reducing acute glutamatergic activity and acute antidepressant effects. nature.com/articles/s4159…

🧠 Our new study is out in Nature Communications! DNMT1 regulates the migration of cortical interneurons, with implications for cortical layering and function — and potentially neuropsychiatric conditions. 🔗 doi.org/10.1038/s41467… Huge thanks to the amazing team/collaborators!

🚨 We're hiring! The Erwin Lab at Flinders University is looking for graduate students and postdocs passionate about neurogenetics, epigenetics & therapeutics. Collaborate with biotech & launch a spinout. 📩 [email protected] 🔗 flinders.edu.au/people/jennife…

Courage is rarely priced in. This is true of markets, public or private, elections, movements, or any organization that seeks to grow. When you see a courageous act, it can take many months for scale to follow and the narrative to catch up. This is because analysts and experts

LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development dlvr.it/TMdp9S