What makes COVID-19 different from other severe infections? How does dexamethasone work in severe COVID-19? Our paper Nature Medicine from U Calgary takes a deep dive: nature.com/articles/s4159… 🧵 recasting neutrophils as immunotherapeutic targets & access to raw datasets👇(1/15)

New results shed light into the molecular mechanisms of dexamethasone action underlying its therapeutic benefit in patients with severe #COVID19 Jeff Biernaskie @ucalgaryvetmed UCalgaryMedicine @NicoleLRosin Sarthak Sinha, MD, PhD nature.com/articles/s4159…

#UCalgary study shows drug used to treat critically ill #COVID19 patients may only benefit males due to the way our immune systems respond to the disease ow.ly/ymqX50GNZhf @ucalgaryvetmed

The results of a study in Nature Medicine shed light on the molecular mechanisms of dexamethasone action, underlying its therapeutic benefit in patients with severe COVID-19. go.nature.com/3oyqvxI

Dexamethasone restrains neutrophils in severe COVID-19 dlvr.it/SDhtXD

Thanks Global Calgary for featuring our charity on your morning news cast! If you are reading this, please take a moment to watch, and consider donating to our charity this holiday season. globalnews.ca/video/rd/289b4…

Hiring a creative & collaborative #postdoc & PhD student for funded positions to study fibroblast-immune interactions during skin regeneration. If interested in wound healing, single cell genomics, mice & reindeer (!) get in touch by email/DM. Please RT! tinyurl.com/4jd4whym

11 years ago Sarthak Sinha, MD, PhD joined my lab for a High School research project. Congratulations to Dr. Sarthak Sinha on his fantastic seminar and successful thesis defence! #proudmentor

Big congratulations to the Calgary Firefighters Burn Treatment Society on being awarded the John Moncrief award at ABA2022 for their incredible leadership and volunteerism towards improving burn care. Incredible group of people. cfbts.org/cfbts-wins-the…

After 6.5 years and countless hours on the microscope🔬, my PhD work from kubeslab is finally out in nature! ✨"A monocyte-leptin-angiogenesis pathway critical for repair post-infection"✨ (1/11) nature.com/articles/s4158…

Check out our new nature paper on Monocyte-leptin-angiogenesis pathway critical for repair post-infection!! Congrats to Dr. Rachel Kratofil 🔬 and colleagues for all the hard work!! Snyder Institute for Chronic Diseases UC PhysPharm UCalgaryMedicine U Calgary

An incredible story led by Rachel Kratofil 🔬 kubeslab Snyder Institute for Chronic Diseases describing a novel monocyte–leptin–angiogenesis pathway that drives repair after skin infection nature! #ProudCollaborator A must-read tweetorial with broad implications for fibrosis and desmoplasia👇

The University of Calgary is inviting applications for a Professor and Canada Research Chair (Tier I) position in Neurodevelopment. Located in one of the world’s most livable cities, it is Canada’s leading next-generation university. Please Retweet! nature.com/naturecareers/…

Our pre-print describing tumor core and leading edge states in oral squamous cell carcinoma (OSCC) using spatial transcriptiomics is now available bioRxiv (biorxiv.org/content/10.110…)! We provide an interactive portal for exploration of data: pboselab.ca/spatial_OSCC/ 🧵↓

Why do some people develop lethal Aspergillosis while most of us breathe Af spores every day without getting sick? Nicole S. Snyder Institute for Chronic Diseases U Calgary define mechanisms of natural resistance and breakdown after COVID, flu, and steroids in the cover story of Science Translational Medicine👇

We're proud to share our work in @JeffBiernaskie's Lab U CalgaryVetMed @UCalgary asking why reindeer antler velvet regenerates after wounding whereas back skin forms scar Cell! doi.org/10.1016/j.cell… JRNLclub: jrnlclub.org/research-films… 🦌Atlas: biernaskielab.ca/reindeer_atlas

Interested in tissue regeneration & need something to get you into the Xmas spirit? Check out our new paper in Cell exploring the mechanisms underlying skin regeneration in reindeer! So proud of Sarthak Sinha, MD, PhD & @HollySparksUCVM who led this work. tinyurl.com/yw29yb5y

Great seminar on work out in Cell today! Sarthak Sinha, MD, PhD leveraged regenerative properties of mice and reindeer antler velvet to identify factors that can promote skin regeneration in humans. Jeff Biernaskie @ucalgaryvetmed U Calgary #JRNLclub jrnlclub.org/research-films…

Also check out a thoughtful commentary by Drs. Dr. ᐯᗩᒪEᖇIE ᕼOᖇᔕᒪEY 🔬 and @Caves_Elizabeth Yale University titled 'Reindeer light the way to scarless wound healing': doi.org/10.1016/j.cell…

Been waiting with anticipation to see this paper.....fascinating use of optimal animal models for the question.....well done!