So this is now officially out! Our studies Rosenblum Lab demonstrate how interactions between defined inhibitory and excitatory cortical neurons undelie the coherency of aversive memory retrieval - an evolutionary pre-requisite for animal survival. sciencedirect.com/science/articl…

Happy Easter, Pesach and Ramadan, beautiful weather during Lab trip today to the Carmel mountain and sea after too long time...

Ten years and two countries later, my PhD research at the University of Dundee is now published Molecular Metabolism ! #metabolism #inflammation #cytokines #insulin sciencedirect.com/science/articl…

Using retrograde viral tracing, behavioral analysis, and electrophysiology at the insular cortex, we reveal that the intrinsic properties of BLA-projecting neurons are regulated by innate and learned drives, as a function of certainty of taste valence prediction, but not percept.

How prior knowledge, novelty and valance are integrated in the anterior insula during real life experiences? Excellent Kumar and Adonis led the project. Adonis Yiannakas Dr. Sailendrakumar Kolatt Chandran biorxiv.org/content/10.110…

Looks like ethanol-driven taste aversion memories also rely on parvalbumin inhibition on insular cortex neurons projecting to the amygdala. biorxiv.org/content/10.110…

Thrilled to share our latest research on intra-insular circuits and their role in immune regulation and memory! We reveal how brain circuits encode immune memories, offering new insights into neuroimmune communication and how the brain can shape immunity. nature.com/articles/s4159…

A bidirectional anterior-posterior insula circuit mediates the conditioned immune response, wherein a sensory stimulus, after pairing with an immunomodulatory agent, evokes aversive behavior and an anticipatory immune response Rosenblum Lab Federica Cruciani Dr. Sailendrakumar Kolatt Chandran kobi rosenblum

Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit nature.com/articles/s4159…

Our latest research on ERK1/2 nuclear translocation in extinction learning is now published! We used viral-mediated peptide delivery to block nuclear ERK1/2 selectively. ERK1/2 nuclear translocation is critical for memory extinction. RosenblumLab molecularbrain.biomedcentral.com/articles/10.11…